Protein Alignment Zasp66 and SLC9A3R1

DIOPT Version :9

• Sequence 1: NP_729395.2
• Gene: Zasp66 / 38988
• FlyBaseID: FBgn0035917
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_004243.1
• Gene: SLC9A3R1 / 9368
• HGNCID: 11075
• Length: 358
• Species: Homo sapiens
• Alignment Length: 358
• Identity: 72/358 - (20%)
• Similarity: 119/358 - (33%)
• Gaps: 120/358 - (33%)

  Fly    41 PLPS-PCRRRSSSGLKKRVHFADEQNVG-----VQVGSPAH-GELLRGDIISKIGEYDARDLSHA 98
            |||. .|..:..:|....:| .::..:|     |:.||||. ..||.||.:.::...:....:|.
Human    10 PLPRLCCLEKGPNGYGFHLH-GEKGKLGQYIRLVEPGSPAEKAGLLAGDRLVEVNGENVEKETHQ 73

  Fly    99 DAQQLFRGAGNEIRLVV---HRDNKI--------------------------AYTQGATQEAGPG 134
            ......|.|.|.:||:|   ..|.::                          |..|||..|..|.
Human    74 QVVSRIRAALNAVRLLVVDPETDEQLQKLGVQVREELLRAQEAPGQAEPPAAAEVQGAGNENEPR 138

  Fly   135 SRSNSTLPPVTPDLMPH-----RGPSPF-------LPGPSHFERAL--QLPVDT---LPQTVFPQ 182
            ....|  .|...:|.|.     :|||.:       ...|..|.|::  ..|.:.   ..|....:
Human   139 EADKS--HPEQRELRPRLCTMKKGPSGYGFNLHSDKSKPGQFIRSVDPDSPAEASGLRAQDRIVE 201

  Fly   183 LNS----------------SGGYEVPSTVFSPKPTRDHQQDVDEEQAAIV-NQPYRTTPLVLP-- 228
            :|.                :||.|....|.      |.:.|...::..:: :|.:...||.:|
Human   202 VNGVCMEGKQHGDVVSAIRAGGDETKLLVV------DRETDEFFKKCRVIPSQEHLNGPLPVPFT 260

  Fly   229 GAKVKKD---APTTESYLRHYPNPAVRAHPGHDYHDSIMKQRVADTMLHKVVGSEADTGRVFHKQ 290
            ..:::|:   ....|:.|.. |.||:                        |..:.:||....:.|
Human   261 NGEIQKENSREALAEAALES-PRPAL------------------------VRSASSDTSEELNSQ 300

  Fly   291 FNSPIGLYSNNNIEDTIRSTVPFATSESNRLKD 323
            .:.|        .:|   ||.|.:||.|:.:.|
Human   301 DSPP--------KQD---STAPSSTSSSDPILD 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	15/47 (32%)
		DUF4749	285..359	CDD:292558	10/39 (26%)
SLC9A3R1	NP_004243.1	PDZ_signaling	12..91	CDD:238492	20/79 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..192		17/79 (22%)
		PDZ_signaling	152..231	CDD:238492	13/78 (17%)
		EBP50_C	235..358	CDD:312529	24/124 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	277..358		17/82 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900