Protein Alignment Zasp66 and PDLIM1

DIOPT Version :9

• Sequence 1: NP_729395.2
• Gene: Zasp66 / 38988
• FlyBaseID: FBgn0035917
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_066272.1
• Gene: PDLIM1 / 9124
• HGNCID: 2067
• Length: 329
• Species: Homo sapiens
• Alignment Length: 403
• Identity: 70/403 - (17%)
• Similarity: 120/403 - (29%)
• Gaps: 176/403 - (43%)

  Fly    63 EQNVGVQVGSP----AHGELLRGDIISKIGEYDARDLSHADAQQLFRGAGNEIRLVVHRDNKIAY 123
            ||.:.:...:|    |...|..||:|:.|...:..:::|.:||...:|..:.:.|.|.|..
Human    25 EQPLAISRVTPGSKAALANLCIGDVITAIDGENTSNMTHLEAQNRIKGCTDNLTLTVARSE---- 85

  Fly   124 TQGATQEAGPGSRSNSTLPPVTPDLMPHRGPSPFLPGPSHFERALQLPVDTLPQTVFPQLNSSGG 188
                                       |:
Human    86 ---------------------------HK------------------------------------ 87

  Fly   189 YEVPSTVFSPKPTRDHQQDVDEEQAAIVNQPYRTTPLVLPGAKVKKDAPTTESYLRHYPNPAVRA 253
                  |:||..|.:.::           .||:..                   |...|...:
Human    88 ------VWSPLVTEEGKR-----------HPYKMN-------------------LASEPQEVL-- 114

  Fly   254 HPGHDYHDSIMKQRVADTMLHKVVGSEADTGRVFHKQFNSPIGLYSNNNI---EDTIRSTVPFAT 315
            |.|..::.|.|....:.        :.:.|.||...|:|:|.||||:.||   .:.:.|....:.
Human   115 HIGSAHNRSAMPFTASP--------ASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASG 171

  Fly   316 SESNRLKDSPL-HRPLPTKLNGYKKTVQYDPRNSETYRAIQEEGGYSNYGQSSPQEVTIPVQTKV 379
            .|:|   ..|| |...|:.|        ...:.||.|:.:||:   ....:...|..:..|..::
Human   172 VEAN---SRPLDHAQPPSSL--------VIDKESEVYKMLQEK---QELNEPPKQSTSFLVLQEI 222

  Fly   380 YQ------PNRLVPGKKPVSAPVSRPPYNVVNT-------------------------HDE---- 409
            .:      ||: ..|.:.|.|||::...::.|.                         |.|
Human   223 LESEEKGDPNK-PSGFRSVKAPVTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVC 286

  Fly   410 -----NIRQSGSF 417
                 |::|.|.|
Human   287 TDCGTNLKQKGHF 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	12/50 (24%)
		DUF4749	285..359	CDD:292558	24/77 (31%)
PDLIM1	NP_066272.1	PDZ_signaling	10..82	CDD:238492	14/56 (25%)
		DUF4749	138..230	CDD:318205	26/105 (25%)
		LIM_CLP36	260..311	CDD:188832	6/40 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	71	1.000	Inparanoid score	I5310
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24214
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.180