DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and YHP1

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_010739.3	Gene:	YHP1 / 852062	SGDID:	S000002859	Length:	353	Species:	Saccharomyces cerevisiae

Alignment Length:	364	Identity:	75/364 - (20%)
Similarity:	112/364 - (30%)	Gaps:	107/364 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 SNSTLPPVTPDLMPHRGPSPFLPGPSHFERALQLPVDTLPQTVFPQLNSSGGYEVPSTVFS---- 197
            |.:|:.|..|:::.....|||             .:.|||.|.||. :..|...:|....|
Yeast     3 SRNTVLPSLPNIITGTSNSPF-------------QLHTLPNTNFPS-DDQGDIRLPPLAASAHIV 53

  Fly   198 -------------PKPTRDHQQDVDEEQAAIVNQPYRT--TPLVLPGAKVKKDAPTTESYLRHYP 247
                         .:|.|...|.||     .::|...|  |||..| .|:...:|.|
Yeast    54 RPVVNIYKSPCDEERPKRKSPQAVD-----FLSQRVTTSMTPLSKP-KKLSSHSPFT-------- 104

  Fly   248 NPAVRA----HPGHDYHDSIMKQRV------ADTMLHKVVGSEADTGRVF--HKQFNSPIGLYSN 300
             |.||.    .|....| |..|..:      |..:|......|......|  |.|...|......
Yeast   105 -PTVRVCSKEQPPQSMH-SYKKVNILTPLSAAKAVLTPTTRKEKKRSFAFITHSQETFPKKEPKI 167

  Fly   301 NNIEDTIRSTVPFATSESNRLKDSPLHRPLPTK---------LNGYKKTVQYDPRNSETYRAIQE 356
            :|.....|.....::.|...|:.:....|.|.|         .|..:|:||...:|........:
Yeast   168 DNARLARRKRRRTSSYELGILQTAFDECPTPNKAKRIELSEQCNMSEKSVQIWFQNKRQAAKKHK 232

  Fly   357 EGG-------YSN-------YGQSSPQEVTIPVQTK-----------------VYQPNRLVPGKK 390
            ..|       :||       |..::.:..:.|..||                 :::.:.:.|.|.
Yeast   233 NSGNTSHCKVHSNDSMSMISYSDAALEITSTPTSTKEAITAELLKTSPANTSSIFEDHHITPCKP 297

  Fly   391 PVSAPVSRPPYNVVNT-----HDENIRQ-SGSFNRLMYS 423
            .......|....|..|     |.|.|:. .|..|||.::
Yeast   298 GGQLKFHRKSVLVKRTLSNTGHSEIIKSPKGKENRLKFN 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558	16/84 (19%)
YHP1	NP_010739.3	COG5576	123..278	CDD:227863	27/154 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030