Protein Alignment Zasp66 and Pard3

DIOPT Version :9

• Sequence 1: NP_729395.2
• Gene: Zasp66 / 38988
• FlyBaseID: FBgn0035917
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_112514.1
• Gene: Pard3 / 81918
• RGDID: 620374
• Length: 1337
• Species: Rattus norvegicus
• Alignment Length: 463
• Identity: 88/463 - (19%)
• Similarity: 151/463 - (32%)
• Gaps: 173/463 - (37%)

  Fly    61 ADEQNVGVQVGSPAHGE---LLRGDIISKIGEYDARDLSHADAQQLFRGAGNEIRLVVHRDNKIA 122
            |.:.|..:||....||:   |...||:..:.:...|.::..|.|....|.          |...|
  Rat    39 AKDPNYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGG----------DGTSA 93

  Fly   123 YTQGATQE-----AGPGSRSNSTLPP--------VTPDL----MP---HRGPSPFLPGPS----- 162
            .:.| ||.     :..|:.:.|...|        |||.:    ||   .|...|.|.|.|
  Rat    94 SSTG-TQSPEIFGSELGTNNVSAFRPYQTTSEIEVTPSVLRANMPLHVRRSSDPALTGLSTSVSD 157

  Fly   163 -HF---ERALQLPVDTLPQTVFPQLNSSGGYEVPSTVFSPKPTRDHQQDVDEEQAAIVNQPYRTT 223
             :|   |.:.:.|.         :.:::.|:...:|..||| |.|.::|          :.||:.
  Rat   158 NNFSSEEPSRKNPT---------RWSTTAGFLKQNTTGSPK-TCDRKKD----------ENYRSL 202

  Fly   224 PLVLPGAKVKKDAPTTESYLRHYPNPAVRA-HPGHDYHDSIMKQRVADTMLHKVVGSEADTGRVF 287
            |        :..:..:..:.|.....::.| ||        |..|..:.......|:|.|:.||
  Rat   203 P--------RDPSSWSNQFQRDNARSSLSASHP--------MVDRWLEKQEQDEEGTEEDSSRV- 250

  Fly   288 HKQFNSPIG-------LYSNNNIEDTIR-------------STVPFA------------------ 314
                 .|:|       ...|.:::|.::             ..|||:
  Rat   251 -----EPVGHADTGLENMPNFSLDDMVKLVQVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGG 310

  Fly   315 -TSESN---------RLKDSPL-HRPLPTKLNGYKKTVQ--------YDPRNSETYRAI--QEEG 358
             ..:.|         |:.|..| :|......:.:::.::        ....|.|.|..:  :|..
  Rat   311 KAEQENLFHENDCIVRINDGDLRNRRFEQAQHMFRQAMRARVIWFHVVPAANKEQYEQLSQREMN 375

  Fly   359 GYS--------------NYGQSSPQEVTIPVQTKVYQPNRLV-----------PGKKPVSAPVSR 398
            .||              :...::||  .:|...::.||...:           ...||.:||...
  Rat   376 NYSPGRFSPDSHCVANRSVANNAPQ--ALPRAPRLSQPPEQLDAHPRLPHSAHASTKPPTAPALA 438

  Fly   399 PPYNVVNT 406
            || ||::|
  Rat   439 PP-NVLST 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	11/49 (22%)
		DUF4749	285..359	CDD:292558	18/132 (14%)
Pard3	NP_112514.1	DUF3534	1..146	CDD:288873	27/117 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	81..109		7/38 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..263		31/161 (19%)
		PDZ_signaling	272..347	CDD:238492	8/74 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..441		11/46 (24%)
		PDZ_signaling	465..544	CDD:238492
		PDZ_signaling	588..681	CDD:238492
		Interaction with PRKCI and PRKCZ. /evidence=ECO:0000269|PubMed:9763423	712..936
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	866..888
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	932..1015
		Interaction with FRMD4A. /evidence=ECO:0000250|UniProtKB:Q99NH2	935..1337
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1028..1055
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1110..1271
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1284..1337

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900