DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and Pdzk1

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_113900.1	Gene:	Pdzk1 / 65144	RGDID:	70924	Length:	523	Species:	Rattus norvegicus

Alignment Length:	398	Identity:	82/398 - (20%)
Similarity:	139/398 - (34%)	Gaps:	114/398 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 KKRVHFAD--EQNVGVQVGSPAHGELLRGDIISKIGEYDARDLSHADAQQLFRGAGNEIR-LVVH 116
            ||.|...|  .|.|.::.|      :|..|.:.::...:..:.||.:..:....:|:.|. |:|.
  Rat   155 KKGVFLTDITPQGVAMKAG------VLADDHLIEVNGENVENASHEEVVEKVTKSGSRIMFLLVD 213

  Fly   117 RDNKIAYTQGATQEAGPGSRSNSTLPPVTPDLMPHRGPSPFLPGPSHFERALQLPVDTLPQTVFP 181
            ::....:::..|    |..|..::|     .|:||:                       |:.|..
  Rat   214 KETARCHSEQKT----PFKRETASL-----KLLPHQ-----------------------PRVVVI 246

  Fly   182 QLNSSG-GYEVPSTVFSPKPTRDHQQDVDEEQAAIVNQPYRTTPLVLPGAKVKKDAPTTESYLRH 245
            :..|:| |:.:.:   .|           |::..|:..       :.||      :|...:.|::
  Rat   247 KKGSNGYGFYLRA---GP-----------EQKGQIIKD-------IEPG------SPAEAAGLKN 284

  Fly   246 YPNPAVRAHPGHDY----HDSI--MKQRVADTMLHKVVGSEADTGRVFHKQFNSPIGLYSNNNIE 304
              |..|.|..|...    |||:  |.:...|.....|:..|||  |::.....||: ||..:
  Rat   285 --NDLVVAVNGESVEALDHDSVVEMIRNGGDQTTLLVLDKEAD--RIYSLARFSPL-LYCQS--- 341

  Fly   305 DTIRSTVPFATSESNRLKDSPLHRPLPTKLNGYKKTVQYDPRNSETYRAIQEEGGYS---NYGQS 366
                ..:|     :..:|::|.....|.:..|...|........:..|.|:|:..|.   |..:.
  Rat   342 ----QELP-----NGSVKEAPAPISAPLEAPGSATTEDVGDHKPKLCRLIKEDDSYGFHLNAIRG 397

  Fly   367 SPQEVTIPVQ-----TKVYQPNR----LVPGKKPVSAPVSRPPYNVVNTHDENIRQSGSFNRLMY 422
            .|......||     .|....|.    .|.|:.     |...||:.|   .|.|:.||....|:
  Rat   398 QPGSFVKEVQQGGPADKAGLENEDIIIEVNGEN-----VQDEPYDRV---VERIKSSGEHVTLL- 453

  Fly   423 SVIGATEY 430
             |.|...|
  Rat   454 -VCGKVAY 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	8/47 (17%)
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558	14/73 (19%)
Pdzk1	NP_113900.1	PDZ_signaling	7..87	CDD:238492
		PDZ	132..212	CDD:214570	14/62 (23%)
		PDZ_signaling	242..320	CDD:238492	20/106 (19%)
		PDZ	375..455	CDD:214570	21/89 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	479..523
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900