DRSC/TRiP Functional Genomics Resources

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Protein Alignment Zasp66 and Pdzd2

DIOPT Version :9

Sequence 1:NP_729395.2 Gene:Zasp66 / 38988 FlyBaseID:FBgn0035917 Length:430 Species:Drosophila melanogaster
Sequence 2:XP_038959013.1 Gene:Pdzd2 / 65034 RGDID:619958 Length:2818 Species:Rattus norvegicus


Alignment Length:517 Identity:102/517 - (19%)
Similarity:152/517 - (29%) Gaps:177/517 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MTTSRSSASASFSRPAFWKVPGYELPTSYRPQPTPKPPLVPLPSPCRRRSSSGLKKRVHFADEQN 65
            |....:|:|:|...||       :||.|::.:.:..|..|.:|..                    
  Rat  2132 MAKPATSSSSSLQLPA-------KLPESFQGKSSQMPASVGVPKN-------------------- 2169

  Fly    66 VGVQVGSPAHGELLRGDIISKIGEYDARDLSHADAQQLFRGAGNEIRLVVHRDNKIAYTQGATQE 130
             ||.:|.                                  ||.|......|             
  Rat  2170 -GVPIGL----------------------------------AGEESPYFTPR------------- 2186

  Fly   131 AGPGSRSNSTLPPVTPDLMPHRGPSPFLPGPSHFERALQLPV---DTLPQTVFPQLNSSGGYEV- 191
              |.:|:.| :|..........||||.  .|||..:..|:|.   ....:|.....|..|.|.| 
  Rat  2187 --PATRTYS-MPAQFSSHFGREGPSPH--SPSHSPQDPQVPAMGGKLSEKTAKGVTNGQGVYSVK 2246

  Fly   192 ----PSTVFSPKPTRDHQQDVDEEQAAIV---------------NQPYRTTPLVLPGAKVK---- 233
                .|...||...||  ...|.|.:.::               :.|:.:|.......::|    
  Rat  2247 PLLETSKNLSPVDGRD--VSADPETSCLIPDKVKVTRRQYCCEQSWPHESTSFFSVKQRIKSFEN 2309

  Fly   234 ---KDAPT----TESYLRHYPNPAVRAH-----PGHDYHDSIMKQRVADTMLHKVVGSEADTGRV 286
               .|.||    |..:|.....|.:...     |.....|  |..|.....|.....|:::...:
  Rat  2310 LANSDRPTAKCATSPFLSVSSKPPINRRSSGSIPSGSPSD--MTSRSLRRSLSSCSESQSEASSL 2372

  Fly   287 FHKQFNSPIGL---YSNNNIEDTI---------RSTVPFA--------TSESNRLKDSPLH-RPL 330
            ..:...||..:   .|..|..||.         :|.||..        .|.|.|.|.|..| :|.
  Rat  2373 LPQMTKSPSSMTLTVSRQNPPDTSNKGPSPDPKKSLVPVGIPTSTVSPASPSKRNKSSVRHAQPS 2437

  Fly   331 P---TKL---------------NG-----------YKKTVQYDPRNSETYRAIQEEG----GYSN 362
            |   :||               ||           :|..::..||.|:..:|....|    |:::
  Rat  2438 PVSRSKLQELRTLSMPDLDKLCNGEDDSASPGAVLFKTQLEITPRRSKGSQATSPAGSPARGHAD 2502

  Fly   363 YGQSSPQEVTIPVQTKVYQPNRLVPGKKPVSAPVSRPPYNVVNTHDENIRQSGSFNRLMYSV 424
            :..|:.....:...|:.|......|..:|..|..||.....|.........|.|.:||:.||
  Rat  2503 FNGSTFLSCPMNGGTRAYTKGNSPPASEPAIATGSREEGESVWATPSGKSWSVSLDRLLASV 2564

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Zasp66NP_729395.2 PDZ_signaling <68..115 CDD:238492 5/46 (11%)
DUF4749 285..359 CDD:292558 27/127 (21%)
Pdzd2XP_038959013.1 PDZ_signaling 335..416 CDD:238492
PDZ_signaling 590..671 CDD:238492
PDZ_signaling 729..813 CDD:238492
PHA03247 <985..1446 CDD:223021
PDZ_signaling 2603..2677 CDD:238492
PDZ_signaling 2731..2813 CDD:238492
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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