DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Zasp66 and SHOX

DIOPT Version :9

Sequence 1:NP_729395.2 Gene:Zasp66 / 38988 FlyBaseID:FBgn0035917 Length:430 Species:Drosophila melanogaster
Sequence 2:NP_000442.1 Gene:SHOX / 6473 HGNCID:10853 Length:292 Species:Homo sapiens


Alignment Length:34 Identity:12/34 - (35%)
Similarity:18/34 - (52%) Gaps:10/34 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   346 RNSETYRAIQEEG-------GYSNYGQSSPQEVT 372
            ::|.|||.:.|.|       |.|:   ||.|::|
Human    30 KDSITYREVLESGLARSRELGTSD---SSLQDIT 60

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Zasp66NP_729395.2 PDZ_signaling <68..115 CDD:238492
DUF4749 285..359 CDD:292558 6/19 (32%)
SHOXNP_000442.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..34 1/3 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 100..119
Homeobox 120..174 CDD:395001
SH3-binding. /evidence=ECO:0000255 242..249
OAR 272..288 CDD:397759
OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138 274..287
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R6207
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.030

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