Protein Alignment Zasp66 and PDLIM2

DIOPT Version :9

• Sequence 1: NP_729395.2
• Gene: Zasp66 / 38988
• FlyBaseID: FBgn0035917
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_067643.3
• Gene: PDLIM2 / 64236
• HGNCID: 13992
• Length: 602
• Species: Homo sapiens
• Alignment Length: 492
• Identity: 98/492 - (19%)
• Similarity: 138/492 - (28%)
• Gaps: 222/492 - (45%)

  Fly    13 SRPAFWKVPGYEL---PTSYR-------PQP--------TPKPPLVP-----LPSPCRR----RS 50
            :|||   :||..|   |.|.|       |.|        .|:..|.|     |..|.||    ||
Human   158 ARPA---LPGAGLLSAPLSARNPGLVRGPAPWSLASAGAPPRAALSPAGALLLQPPARRVLCPRS 219

  Fly    51 SSGLK------------KRVHFADEQN------VGVQVGSPA----------------------- 74
            ..|.:            :....|:..:      :.|.|..||
Human   220 EGGSRTGRAGPSGWAPPRGARSAESTDRLKGMALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAE 284

  Fly    75 -----HGELLRGDIISKIGEYDARDLSHADAQQLFRGAGNEIRLVVHRDNKIAYTQGATQ----- 129
                 ..:|..||||..|....|..:.||:||...|.:.:.:||.:.|..  |.:.|.|.
Human   285 RGKAKDADLRPGDIIVAINGESAEGMLHAEAQSKIRQSPSPLRLQLDRSQ--ATSPGQTNGDSSL 347

  Fly   130 ---------------EAGPGSRSNSTLPPVTPDLMPHRGPSPFLPGPSHFERALQLPVDTLPQTV 179
                           |:....||:.:.|   ..|.|..| |||.|.||    :..|..:......
Human   348 EVLATRFQGSVRTYTESQSSLRSSYSSP---TSLSPRAG-SPFSPPPS----SSSLTGEAAISRS 404

  Fly   180 FPQLNSSGGYEVPSTV-FSPKPTRDHQQDVDEEQAAIVNQPYRTTPLVLPGAKVKKDAPTTESYL 243
            |..|..|.|......: :|.:|        ...||.: .:...:..||||
Human   405 FQSLACSPGLPAADRLSYSGRP--------GSRQAGL-GRAGDSAVLVLP--------------- 445

  Fly   244 RHYPNPAVRAHPGHDYHDSIMKQRVADTMLHKVVGSEADTGRVFHKQFNSPIGLYSNNNIEDTIR 308
               |:|..                                                        |
Human   446 ---PSPGP--------------------------------------------------------R 451

  Fly   309 STVPFATSESNRL---KDSPLHRPLPTKLNGYKKTVQYDPRNSETYRAIQ------EEGGYSNYG 364
            |:.|...||...|   :||.:.:.|.....|     :..||.|.::|.:|      |.||
Human   452 SSRPSMDSEGGSLLLDEDSEVFKMLQENREG-----RAAPRQSSSFRLLQEALEAEERGG----- 506

  Fly   365 QSSPQEVTIPVQTKVYQPNRLVP-GKKPVSAPVSRPP 400
                        |..:.|:.|.| ...|.|..::.||
Human   507 ------------TPAFLPSSLSPQSSLPASRALATPP 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	18/74 (24%)
		DUF4749	285..359	CDD:292558	16/82 (20%)
PDLIM2	NP_067643.3	PDZ_signaling	259..330	CDD:238492	16/70 (23%)
		DUF4749	<462..505	CDD:292558	11/47 (23%)
		LIM_Mystique	536..588	CDD:188833

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	71	1.000	Inparanoid score	I5310
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24214
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.150