DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and mxtx2

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_001073284.1	Gene:	mxtx2 / 58078	ZFINID:	ZDB-GENE-000710-6	Length:	296	Species:	Danio rerio

Alignment Length:	166	Identity:	44/166 - (26%)
Similarity:	61/166 - (36%)	Gaps:	50/166 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 SGLKKRVHFADEQNVGVQVGSPAHGELLRGDIISKIGEYDARDLSHADAQQLFRGAG-NEIRLVV 115
            :|.:||..|..|           |.|||:  :...:..|....:    .:.|.:..| .|.|:.|
Zfish    21 AGRRKRTSFTKE-----------HLELLK--MAFNVDPYPGISV----RESLSQATGLPESRIQV 68

  Fly   116 HRDNKIAYT-QGATQEAGPGSRSNSTLPPVTPDLMPHRGPSPFLP------GPSHFERALQ-LPV 172
            ...||.|.| :....::.|...:.|.|            ||||||      |.|..:|.:| .|.
Zfish    69 WFQNKRARTLKNRAIQSSPQLDNKSPL------------PSPFLPPHMASVGVSAQQRGIQESPF 121

  Fly   173 D-----TLPQ-TVFPQLNSSGGYEVPSTVFSPKPTR 202
            :     |.|| ..||    ...|..|  |..|:.||
Zfish   122 NIQMSQTSPQHFTFP----PSDYSTP--VVKPRQTR 151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	9/47 (19%)
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558
mxtx2	NP_001073284.1	HOX	22..76	CDD:197696	17/70 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030