DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and pdlim4

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_001036161.1	Gene:	pdlim4 / 569404	ZFINID:	ZDB-GENE-070308-5	Length:	349	Species:	Danio rerio

Alignment Length:	344	Identity:	65/344 - (18%)
Similarity:	109/344 - (31%)	Gaps:	133/344 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 AHGELLRGDIISKIGEYDARDLSHADAQQLFRGAGNEIRLVVHRDNKIAYTQGATQEAGPGSRSN 138
            |...|..||.|..|.......::|.:||...:...:::.|.:.|..| |:
Zfish    39 AQSNLSPGDTILAINGESTESMTHMEAQNRIKACTDQLVLAICRSGK-AW--------------- 87

  Fly   139 STLPPVTPDLMPHRGPSPFLPGPSHFERALQLPVDTLPQTVFPQLNSSGGYEVPSTVFSPKPTRD 203
                  :|..|.....|||.|              ||              |..|..|.|
Zfish    88 ------SPTGMEELKTSPFSP--------------TL--------------ESDSQTFRP----- 113

  Fly   204 HQQDVDEEQAAIVNQPYRTTPLVLPGAKVKKDAPTTESYLRHYPNPAVRAHPGHDYHDSIMKQRV 268
                        ::..|..||        |..:|         .:|...|.|   |::.
Zfish   114 ------------ISSGYSPTP--------KSPSP---------KSPITGAVP---YNNG------ 140

  Fly   269 ADTMLHKVVGSEADTGRVFHKQFNSPIGLYSNNNIEDTIRSTV-------PFATSESNRLKDSPL 326
                     ||        ...:|:|.||||:||....:...:       |.:.|....:..|..
Zfish   141 ---------GS--------RPVYNNPAGLYSHNNGNGALPKQMSGLSLGSPHSFSPEPPVNSSGN 188

  Fly   327 HRPLPTKLNGYKKTVQYD-----PRNSETYRAIQ-----EEGGYSNYGQSSPQEVTIPVQTKVYQ 381
            .....|:.:.|:..:.|:     |:.|.:::.:|     |:||.|...:|..:.:..||::.|.:
Zfish   189 RNGFDTQSDVYRMLLDYEEPVSAPKQSGSFKYLQGILEAEDGGVSPVDRSGVRGLRSPVKSPVPK 253

  Fly   382 PNRLVPGKKPVSAPVSRPP 400
            ..      .|::||::..|
Zfish   254 LG------SPITAPLAPIP 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	10/40 (25%)
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558	18/90 (20%)
pdlim4	NP_001036161.1	PDZ_signaling	3..78	CDD:238492	9/38 (24%)
		DUF4749	146..233	CDD:292558	20/86 (23%)
		LIM_RIL	274..326	CDD:188835
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	72	1.000	Inparanoid score	I5287
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24214
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.150