DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and grid2ipb

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	XP_009304908.1	Gene:	grid2ipb / 559717	ZFINID:	ZDB-GENE-040724-161	Length:	1383	Species:	Danio rerio

Alignment Length:	383	Identity:	75/383 - (19%)
Similarity:	107/383 - (27%)	Gaps:	148/383 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 PGYELPTSYRPQPTP------------KPPLVPLPS------PCRRR------------------ 49
            ||.:..|..:...:|            .||..||||      |.||:
Zfish   669 PGPQFETYQQTVASPDSVDSNPYVSLDSPPASPLPSDELSPLPQRRKLFTFSRPPRSRDTDKFLD 733

  Fly    50 -SSSGLKKRVHFADEQNVGVQVGSPAHGELLRGDIISKIGEYDARDLSHADAQQL------FRGA 107
             .|..|..||:..|:                     .|.||.|..::|..|.|::      ...|
Zfish   734 ALSEQLGHRVNIVDD---------------------FKGGENDYEEMSFQDEQEVNMLPHELSSA 777

  Fly   108 GNEIRLVVHRDNKIAYTQGATQEAGPGSRSNSTLPPVTPDLMPHRGPSPFLPGPSHFERALQLPV 172
            .:|..........::|:.|:.....|    ..:.||..|.|.....|||....|.|
Zfish   778 SSEDHSSSDDSTSVSYSSGSDHIPPP----PQSPPPPPPPLQFTDSPSPLPITPEH--------- 829

  Fly   173 DTLPQTVFPQLNSSGGYEVPSTVFS--------PKPTRDHQQD---------VDEEQAAIVNQPY 220
              |||              |...|.        |.|.|....:         ..||..|..:.|.
Zfish   830 --LPQ--------------PPPAFQHHPIIAPPPPPPRPFLANRPSLHKVLPTREELRAQHSHPR 878

  Fly   221 RTTPLVLPGAKVKKDAPTTESYLR-HYP--------NPAVRAHPGHDYHDSIMKQRVADTMLHKV 276
            |::|           .|:::..|: |.|        :|.....|.|........|..:.::....
Zfish   879 RSSP-----------QPSSQPILQLHQPKAHPILQSSPHTSPQPPHTSAQHTRLQHPSQSIYQSQ 932

  Fly   277 VGSEADTGRVFHKQ---FNSPIGLYSNNNIEDTIRSTVPFATSESNRLKDSPLHRPLP 331
            ..:...|.....||   .:.|    |..:.|.|:.|.||           .|...|||
Zfish   933 QTTVPRTSPSLTKQKSLHSQP----SQQSFEGTLSSKVP-----------PPPPPPLP 975

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	9/52 (17%)
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558	13/50 (26%)
grid2ipb	XP_009304908.1	PDZ_signaling	9..69	CDD:238492
		PDZ_signaling	80..156	CDD:238492
		HN_L-delphilin-R1_like	183..262	CDD:259820
		PDZ_signaling	335..410	CDD:238492
		HN_L-delphilin-R2_like	451..530	CDD:259821
		FH2	995..1360	CDD:280362
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900