DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and gsc

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_001016704.1	Gene:	gsc / 549458	XenbaseID:	XB-GENE-486771	Length:	243	Species:	Xenopus tropicalis

Alignment Length:	228	Identity:	48/228 - (21%)
Similarity:	69/228 - (30%)	Gaps:	60/228 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 PAHGELLRGDIISKIGE--YDARDLSH------ADAQQLFRGAGNEIRLVVHRDNKIAYTQ---- 125
            |.:|.:    :.|.:||  |...|.|.      |....|....|:.:..     |...|.|
Frog    25 PQNGPM----VFSSLGESLYGPADYSGFYNRAVAPTSTLQAVTGSRLGF-----NNYYYGQLHVQ 80

  Fly   126 --------GATQEAGPGSRSNSTLPPVTPDLMPHRGPSPFLPGPSHFERALQLPVDTLPQTVFPQ 182
                    ||.|..  |::..|.:||.|    .:.|....|..|...:....:.|.||.:|....
Frog    81 TPMGPSCCGAVQSL--GTQQCSCVPPAT----AYDGAGSVLMPPVPHQMLPYMNVGTLSRTELQL 139

  Fly   183 LNSSGGYEVPSTVFSPKPTRDHQQDVDEEQAAIVNQPYRTTPLVLPGAKVKKDAPTTESYLRHYP 247
            ||.          ...:..|.|:....:||...:...::.|..        .|..|.|...|
Frog   140 LNQ----------LHCRRKRRHRTIFTDEQLEALENLFQETKY--------PDVGTREQLAR--- 183

  Fly   248 NPAVRAHPGHDYHDSIMKQRVADTMLHKVVGSE 280
                |.|...:..:...|.|.|.....|...||
Frog   184 ----RVHLREEKVEVWFKNRRAKWRRQKRSSSE 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	11/49 (22%)
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558
gsc	NP_001016704.1	Homeobox	151..204	CDD:278475	13/67 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030