DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and Pdlim1

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_059061.1	Gene:	Pdlim1 / 54133	RGDID:	68324	Length:	327	Species:	Rattus norvegicus

Alignment Length:	400	Identity:	75/400 - (18%)
Similarity:	123/400 - (30%)	Gaps:	172/400 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 EQNVGVQVGSP----AHGELLRGDIISKIGEYDARDLSHADAQQLFRGAGNEIRLVVHRDNKIAY 123
            ||.:.:...:|    |...|..||:|:.|...|...::|.:||...:|..:.:.|.|.|..:..:
  Rat    25 EQPLAISRVTPGSKAAIANLCIGDLITAIDGEDTSSMTHLEAQNKIKGCVDNMTLTVSRSEQKIW 89

  Fly   124 TQGATQEAGPGSRSNSTLPPVTPDLMPHRGPSPFLPGPSHFERALQLPVDTLPQTVFPQLNSSGG 188
            :...|:|   |.|                  .|:           ::.:.:.||.|. .:.|:
  Rat    90 SPLVTEE---GKR------------------HPY-----------KMNLASEPQEVL-HIGSA-- 119

  Fly   189 YEVPSTVFSPKPTRDHQQDVDEEQAAIVNQPYRTTPLVLPGAKVKKDAPTTESYLRHYPNPAVRA 253
                           |.:..         .|:..:|           ||.|
  Rat   120 ---------------HNRSA---------MPFTASP-----------APGT-------------- 135

  Fly   254 HPGHDYHDSIMKQRVADTMLHKVVGSEADTGRVFHKQFNSPIGLYSNNNIEDTIRSTVPFATSES 318
                                           ||...|:|||.||||:.||.: ..:.|...||.|
  Rat   136 -------------------------------RVITNQYNSPTGLYSSENISN-FNNAVESKTSAS 168

  Fly   319 NRLKDS-PLHRPLPTKLNGYKKTVQYDPRNSETYRAIQEEGGYSNYGQSSPQEVTIPVQTKVYQ- 381
            ....:| |..:|.|:  .|.     ...:.||.|:.:||:   ....:...|..:..|..::.:
  Rat   169 GEEANSRPSAQPHPS--GGL-----IIDKESEVYKMLQEK---QELNEPPKQSTSFLVLQEILES 223

  Fly   382 -----PNRLVPGKKPVSAPVSRPPYNVVNT-------------------------HDE------- 409
                 ||: ..|.:.|.|||::...:|.|.                         |.|
  Rat   224 DGKGDPNK-PSGFRSVKAPVTKVAASVGNAQKLPICDKCGTGIVGVFVKLRDHHPHPECYVCTDC 287

  Fly   410 --NIRQSGSF 417
              |::|.|.|
  Rat   288 GINLKQKGHF 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	13/50 (26%)
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558	26/74 (35%)
Pdlim1	NP_059061.1	PDZ_signaling	5..81	CDD:238492	15/55 (27%)
		DUF4749	136..228	CDD:292558	28/102 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..186		8/26 (31%)
		LIM_CLP36	258..309	CDD:188832	5/39 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	71	1.000	Inparanoid score	I5207
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24214
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.150