DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Zasp66 and pdlim3

DIOPT Version :9

Sequence 1:NP_729395.2 Gene:Zasp66 / 38988 FlyBaseID:FBgn0035917 Length:430 Species:Drosophila melanogaster
Sequence 2:XP_012814883.2 Gene:pdlim3 / 448291 XenbaseID:XB-GENE-942925 Length:361 Species:Xenopus tropicalis


Alignment Length:385 Identity:76/385 - (19%)
Similarity:133/385 - (34%) Gaps:126/385 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 PKPPLVPLPSPCRRRSSSGLKKRVHFADEQNVG-VQVGSPAH-GELLRGDIISKIGEYDARDLSH 97
            |:..::|.|:|...|.:.|    :.|.....:. :..||.:. ..|..||:|..|..:...:::|
 Frog     2 PQNVVLPGPAPWGFRLTGG----IDFNQPLIISRITPGSKSSLANLCPGDVILAIDGFGTENMTH 62

  Fly    98 ADAQQLFRGAGNEIRLVVHR-DNKIAYTQGATQEAGPGSRSNSTLPPVTPDLMPHR---GPSPF- 157
            |:||...:.|.:::.|.:.| :.:|...|..........:.|....|.......|:   .|.|| 
 Frog    63 AEAQDRIKAAMDQLCLKIERAETRIWSPQVCEDGKAHPFKINLEAEPQDLGYFEHKHNIRPKPFI 127

  Fly   158 LPG-------PSHFERALQLPVDTLPQTVFPQLNSSGGYEVPSTVFSPKPTRDHQQDVDEEQAAI 215
            |||       ||.|:                   ...|...||:|.:....     |..|.:||.
 Frog   128 LPGRSSGSSTPSGFD-------------------PGSGRSTPSSVSTVSTI-----DPVELKAAS 168

  Fly   216 VNQPYRTTPLVLPGAKVKKDAPTTESYLRHYPNPAVRAHPGHDYHDSIMKQRVADTMLHKVVGSE 280
            ...|.....:.|||.|                                                 
 Frog   169 RIAPNVPLEMELPGVK------------------------------------------------- 184

  Fly   281 ADTGRVFHKQFNSPIGLYSNNNIEDTIRSTVPFATSESNRLKDSPLHRPLPTKLNGYKKTVQYDP 345
                 :.|.|||:|:.|||::|:.::::..|.....|.     :|:..|:|..:          |
 Frog   185 -----IVHAQFNTPMQLYSDDNVMESLQGQVSTILGEK-----TPMSDPVPPAV----------P 229

  Fly   346 RNSETYRAIQEEGGYSNYGQSSPQEVTIPVQTKVYQ------PNRLVPGKKPVSAPVSRP 399
            : |:.|:.:.::..:.|..:.|.       ..|:.|      |:| ..|.:.|.||:::|
 Frog   230 Q-SDVYKLLHDDTEHPNKPRQSG-------SFKILQDMVDDDPDR-PAGTRSVRAPMTKP 280

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Zasp66NP_729395.2 PDZ_signaling <68..115 CDD:238492 13/47 (28%)
DUF4749 285..359 CDD:292558 17/73 (23%)
pdlim3XP_012814883.2 PDZ_signaling 2..81 CDD:238492 20/82 (24%)
DUF4749 184..263 CDD:406377 22/155 (14%)
LIM_ALP 293..345 CDD:188834
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 64 1.000 Inparanoid score I5190
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R6207
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.080

Return to query results.
Submit another query.