DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Zasp66 and LHX8

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	XP_016856805.1	Gene:	LHX8 / 431707	HGNCID:	28838	Length:	363	Species:	Homo sapiens

Alignment Length:	160	Identity:	35/160 - (21%)
Similarity:	55/160 - (34%)	Gaps:	47/160 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   239 TESYLRHYPNPAVRAHPG---------------HDYHDSIMKQRVADT--MLHKVVGSEADTGRV 286
            ||..:.| |.||.||...               .:..|:...|::|:.  :..:|:.......|.
Human   205 TEQDVNH-PKPAKRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRA 268

  Fly   287 FHKQFNSPIGLYSNNNIEDTIRSTVPFATSESNRLKDSPLHRPLP------TKLNGYKKTVQYDP 345
            .||:..||      |:...|..:.||.:......|::......:|      |.|:.|.
Human   269 RHKKHVSP------NHSSSTPVTAVPPSRLSPPMLEEMAYSAYVPQDGTMLTALHSYM------- 320

  Fly   346 RNSETYRAIQ--------EEGGYSNYGQSS 367
              .:|:.|:.        ...||||.|.||
Human   321 --DDTHAAVHIHLPGRMWRFQGYSNNGSSS 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558	16/87 (18%)
LHX8	XP_016856805.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.030