DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and CG34375

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_001163693.1	Gene:	CG34375 / 42715	FlyBaseID:	FBgn0085404	Length:	568	Species:	Drosophila melanogaster

Alignment Length:	185	Identity:	38/185 - (20%)
Similarity:	65/185 - (35%)	Gaps:	43/185 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 HRDNKIAYTQGATQEAGPGSRSNSTLPPVTPDLMPHRGPSPFLPGPSHFERALQ---LPVDTL-- 175
            |...|:|..:.::.::..|.:.:..|..|..|..|.........|... |:|:|   ||..||
  Fly   218 HNQPKMALAKTSSGKSKCGKQISRQLETVLVDQSPREIRRKSQQGQEQ-EQAVQEAVLPRCTLIK 281

  Fly   176 ---PQTVFPQLNSSGGYEV---PSTVFSPKPTRDHQQDVD----EEQAAIVNQPYRTTPLVLPGA 230
               .:......:..|...:   |....|.|..|....|.|    :|.|.|.|           |.
  Fly   282 VQHQEAAVEHFSEEGHNNMLVKPKLKLSKKSWRITGPDQDGLRCDEVATINN-----------GV 335

  Fly   231 KVKKD-------------APTTESYLRHYPNPAVRAHPGHDYHDSIMKQRVADTM 272
            :|::.             :.::||..::|..|..::...|.|.   :.|.||:.:
  Fly   336 QVQEQQQQQERQQLGHEKSASSESEYQNYHCPTGKSCSSHSYQ---LGQPVANKL 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558
CG34375	NP_001163693.1	PDZ	13..86	CDD:238080
CG34375	NP_001163693.1	RING	129..168	CDD:238093
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900