DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and Syn1

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_001262192.1	Gene:	Syn1 / 40424	FlyBaseID:	FBgn0037130	Length:	627	Species:	Drosophila melanogaster

Alignment Length:	168	Identity:	36/168 - (21%)
Similarity:	64/168 - (38%)	Gaps:	45/168 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 RVHFADEQNVGVQV--------------------GSPAHGELLRGDIISKIGEYDARDLSHADAQ 101
            |:..:|...:|:.:                    ...|.| |..||.|..:...:.||.:|.:|.
  Fly   166 RIIKSDNNGLGISIKGGRENRMPILISKIFRGMAADQAKG-LYVGDAILTVNGEELRDATHDEAV 229

  Fly   102 QLFRGAGNEIRLVVHRDNKIA-YTQGAT---------QEA-----GPGSRSNSTLPPVTPDLMPH 151
            :..:.:|..:.|.|....::. |.:.|:         |.|     |||..::...|..||
  Fly   230 RALKRSGRVVDLEVKFLREVTPYFRKASIISEVGWELQRAFLCPLGPGVPTSPPAPKTTP----- 289

  Fly   152 RGPSPFLP-GPSHFERALQLPVDTLPQTVFPQLNSSGG 188
            |..:.::| ..:|..|.|:. :|  |:....:|:|..|
  Fly   290 RADTRYIPLQLTHLARNLKY-ID--PENRCFELHSPDG 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	12/66 (18%)
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558
Syn1	NP_001262192.1	PH-like	30..>61	CDD:302622
		PDZ_signaling	163..244	CDD:238492	15/78 (19%)
		PHsplit_syntrophin	<293..351	CDD:269960	9/35 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900