DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and CG43707

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_001260005.1	Gene:	CG43707 / 33601	FlyBaseID:	FBgn0263846	Length:	2021	Species:	Drosophila melanogaster

Alignment Length:	495	Identity:	89/495 - (17%)
Similarity:	139/495 - (28%)	Gaps:	214/495 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 YELPTSYRPQPT----PKPPLVPLPSPCRRRSSSGLKKRVHFADEQNVGVQVGSPAHGELLRGDI 83
            ||...|..|.||    |..|    .||||              ||                   :
  Fly   820 YEAKASETPTPTGLRLPSTP----ASPCR--------------DE-------------------L 847

  Fly    84 ISKIGEYDARD-LSHADAQQLFRGAGNEIRLVVHRDNKIAYTQGATQEAGPGSRSNSTLPPVTPD 147
            ::.:..|.:.| |::.:.:....|..||        :::.......::...||.|::.|  :||.
  Fly   848 LANVSTYPSSDSLANDNTRDHSDGIWNE--------SQVTVLTAEQRDISDGSYSSNLL--LTPS 902

  Fly   148 ------LMPHRGPSPFLPGPSHFER-----ALQ---------LPVDTLPQTVFPQLNSSGGYEVP 192
                  |:.|:..|........||.     .||         .|..:.|.:..|.:........|
  Fly   903 SKRKNLLLQHQQRSSVDTDALDFEEQSPTYGLQTLPKIIKTPTPTTSRPTSTQPMMPPPAIAVTP 967

  Fly   193 ST-------VFSPKPTR------------------------------------DHQQDVDEEQAA 214
            ||       :.||.|.|                                    |:.:..|..:.:
  Fly   968 STNQILDSCISSPLPKRSMVARGSVPDARQLMFTSGATKQRHSDASFLPMGAADYARSADISECS 1032

  Fly   215 IVNQPYRT-------TPLVLPGAKVKKDAPTTESYLRHYPNPAVRAHPGHDY------------- 259
            .....|.|       ||:....::::|                  .|.|..:
  Fly  1033 TNTDEYATCTDTSKRTPVSTQSSQLEK------------------THAGSSFESASSLYSMREDL 1079

  Fly   260 --HDSIMKQRVADTMLHKVVGSEADTGRVFHKQFNSPIGLYSNNNIEDTIRSTVPFATSESNRLK 322
              ||.  |:|...|.|.|.             |..||||                   |.:...:
  Fly  1080 LQHDE--KERDKQTTLTKA-------------QLKSPIG-------------------SVAELTR 1110

  Fly   323 DSPLHRPLPTKLNGYKKTVQYDPRNSETYRAIQEEGGYSNYGQSSPQEV--TIPVQTKVYQPNRL 385
            .||.|....|..:|....:.         .||:     |...:|.||.|  ::..|.||.....:
  Fly  1111 KSPSHSISSTTSSGSCPVLG---------AAIK-----SPAKESLPQTVASSVTSQMKVSSVECI 1161

  Fly   386 VPGKKPVSAPVSRPPYNVV---------NTHDENIRQSGS 416
            .||.||....:|....:.|         :.|:|:..:.|:
  Fly  1162 PPGVKPKPDSISEDERSEVRYSSSGYYESPHEEDDEEQGT 1201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	6/47 (13%)
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558	13/73 (18%)
CG43707	NP_001260005.1	PHA03369	<987..1394	CDD:223061	46/281 (16%)
		PDZ_signaling	1702..1775	CDD:238492
		PH	1792..1894	CDD:278594
		PH-like	1792..1893	CDD:302622
		PH-like	1911..2011	CDD:302622
		PH	1921..2014	CDD:278594
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900