DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and baz

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_001036283.1	Gene:	baz / 32703	FlyBaseID:	FBgn0000163	Length:	1520	Species:	Drosophila melanogaster

Alignment Length:	390	Identity:	82/390 - (21%)
Similarity:	131/390 - (33%)	Gaps:	114/390 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 PTPKPPLVPLPSPCRRRSSSGLKKRVHF---ADEQNVGVQV---GSPAHGE--------LLRGDI 83
            ||.||...|:.:..:..::..|.:::..   .....:|..|   .:||.|.        |.||..
  Fly   439 PTRKPHAAPVGTSLQVANTRKLGRKIEIMLKKGPNGLGFSVTTRDNPAGGHCPIYIKNILPRGAA 503

  Fly    84 I--------SKIGEYDARDL---SHADAQQLFRG--AGNEIRLVVHRDNKIA--YTQGATQEAGP 133
            |        .::.|.|...:   :..|...:.||  ||..:|:||.|..::|  ..|.|.:.||.
  Fly   504 IEDGRLKPGDRLLEVDGTPMTGKTQTDVVAILRGMPAGATVRIVVSRQQELAEQADQPAEKSAGV 568

  Fly   134 GSRSNSTLPPVTPDLMPHRGPSPFLPGPSHFERALQLPV--DTLPQTVF-----PQLNSSGGYEV 191
            .         |.|.:.|...|:...|.|       .:||  .:..:::|     .|||.|
  Fly   569 A---------VAPSVAPPAVPAAAAPAP-------PIPVQKSSSARSLFTHQQQSQLNES----- 612

  Fly   192 PSTVFSPKPTRDHQQDVDEEQAAIVNQPYRTTPLVLPGAKVKKDAPTTESYLRHYPNPAVRAH-P 255
                       .|..|...|.||..:.        ||        |::.|:   :....:..| |
  Fly   613 -----------QHFIDAGSESAASNDS--------LP--------PSSNSW---HSREELTLHIP 647

  Fly   256 GHDYHDS----IMKQRVADTMLHKVVGSEADTGRVFHKQFNSPIGLYSNNNIEDTIRSTVPFATS 316
            .||...:    .:|.:....:  ...||.|.:|.....:.:..:|::..|.|...       |.|
  Fly   648 VHDTEKAGLGVSVKGKTCSNL--NASGSSASSGSNGLMKHDGDLGIFVKNVIHGG-------AAS 703

  Fly   317 ESNRLK--DSPLHRPLPTKLNGYKKTVQYDPRNSETYRAIQEEGGYSNYGQSSPQEVTIPVQTKV 379
            ...||:  |..|      .:||.....|.:....||.|.     ...|.....|..:|:.|..|:
  Fly   704 RDGRLRMNDQLL------SVNGVSLRGQNNAEAMETLRR-----AMVNTPGKHPGTITLLVGRKI 757

Fly 380 379
Fly 758 757

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	16/70 (23%)
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558	15/75 (20%)
baz	NP_001036283.1	DUF3534	<62..174	CDD:288873
		PDZ_signaling	341..412	CDD:238492
		CRS1_YhbY	<390..>436	CDD:294440
		PDZ_signaling	462..548	CDD:238492	17/85 (20%)
		PDZ_signaling	<686..753	CDD:238492	18/84 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900