DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and pax6a

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	XP_009296153.1	Gene:	pax6a / 30567	ZFINID:	ZDB-GENE-990415-200	Length:	459	Species:	Danio rerio

Alignment Length:	137	Identity:	29/137 - (21%)
Similarity:	48/137 - (35%)	Gaps:	40/137 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 IAYTQGATQEAGPGSRSN--STLPPVTPDLMPHRGPSPFLPGPSHFERALQLPVDTLPQTVFPQL 183
            :::|.|:.......:.:|  |.|||:                || |..|..||:.       |..
Zfish   347 VSFTSGSMLGRSDTALTNTYSALPPM----------------PS-FTMANNLPMQ-------PSQ 387

  Fly   184 NSSGGYEVPST---------VFSPKPTRDHQQDVDEEQAAIVNQPYRTTPLVLPGAKVKKDAPTT 239
            .||....:|::         .::|...:.|..  .:..||   ....:|.|:.||..|....|.:
Zfish   388 TSSYSCMLPTSPSVNGRSYDTYTPPHMQAHMN--SQSMAA---SGTTSTGLISPGVSVPVQVPGS 447

  Fly   240 ESYLRHY 246
            |..:..|
Zfish   448 EPDMSQY 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558
pax6a	XP_009296153.1	PAX	31..169	CDD:128645
		Homeobox	255..307	CDD:306543
		Retinal	341..>459	CDD:330657	29/137 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030