DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and Pdzd7

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_001099832.2	Gene:	Pdzd7 / 293996	RGDID:	1309882	Length:	1031	Species:	Rattus norvegicus

Alignment Length:	263	Identity:	58/263 - (22%)
Similarity:	93/263 - (35%)	Gaps:	93/263 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 SPCRRRSSSGLKKRVHF---------------ADEQNVGVQVGSPAHGELLRGDIISKIGE---- 89
            :|....|..|:::.||.               ..|..:|:.|....||.|...:.| |:|:
  Rat   197 TPSDSSSEDGVRRIVHLYTTSDDFCLGFNIRGGKEFGLGIYVSKVDHGGLAEENGI-KVGDQVLA 260

  Fly    90 -----YDARDLSHADAQQLFRGAGNEIRLVVHRDNKI-AY-------------TQGATQEAGPGS 135
                 :|  |:||:.|.::.:|. ..|.|.:....:. ||             :.|..|:..|.|
  Rat   261 ANGVRFD--DISHSQAVEVLKGQ-THIMLTIKETGRYPAYKEMVSEYCWLDRLSNGVLQQLSPAS 322

  Fly   136 RSNSTL------PPVTPDLMPH------RGP-SPFLPGPSHFERALQLPVDTLPQTVFPQLNSSG 187
            .|:|::      .|.:...:|.      .|| .|...||. :.||     ||..||. |.:   |
  Rat   323 ESSSSVSSYASSAPCSSGSLPSDRMDVCLGPEDPTSQGPG-WGRA-----DTAMQTE-PDM---G 377

  Fly   188 GYEVPSTVFSPKPTRDHQQDVDEEQAAIVNQPYRTTPLVLPGAKVKKDAPTT----ESYLRHYPN 248
            |..| .|..|.:||                       ::|....::.|.|::    :|.|...|.
  Rat   378 GSRV-ETWCSVRPT-----------------------VILRDTAIRSDGPSSTRHLDSALSESPK 418

  Fly   249 PAV 251
            .|:
  Rat   419 TAL 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	15/55 (27%)
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558
Pdzd7	NP_001099832.2	PDZ_signaling	84..164	CDD:238492
		PDZ_signaling	209..289	CDD:238492	19/83 (23%)
		HN_PDZD7_like	555..632	CDD:259824
		PDZ_signaling	866..954	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900