DRSC/TRiP Functional Genomics Resources

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Protein Alignment Zasp66 and Mpdz

DIOPT Version :9

Sequence 1:NP_729395.2 Gene:Zasp66 / 38988 FlyBaseID:FBgn0035917 Length:430 Species:Drosophila melanogaster
Sequence 2:XP_006238402.1 Gene:Mpdz / 29365 RGDID:3105 Length:2068 Species:Rattus norvegicus


Alignment Length:466 Identity:101/466 - (21%)
Similarity:150/466 - (32%) Gaps:147/466 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 RSSASASFSRP---AFWKVPGYELPTSY---RPQPTPKPPLVPLPSPCRRRSSSGLKKRVHFADE 63
            :::|.:|:|:|   ..|:.|...|..|.   |...:              |.|:|...|..|...
  Rat  1140 QNAAYSSWSQPRRVELWREPSKSLGISIVGGRGMGS--------------RLSNGEVMRGIFIKH 1190

  Fly    64 QNVGVQVGSPA--HGELLRGDIISKIGEYDARDLSHADAQQLFRGAGNE----IRLVVHRDNKIA 122
                |...|||  :|.|..||.|.::...|.||.||..|.:..|.||:.    ::.:|:|..|  
  Rat  1191 ----VLEDSPAGKNGTLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGSPVVFMVQSIVNRPRK-- 1249

  Fly   123 YTQGATQEAGPGSRSNSTLPPVTPDLMPHRGPSPFLPGPSHFERALQLPVDTLPQ---------- 177
                            |.||.:...|.|....|...|    |..:|||..|..|.          
  Rat  1250 ----------------SPLPSLPHSLYPKCSFSSTNP----FAESLQLTSDKAPSQSESESEKAT 1294

  Fly   178 ---------TVFPQLNSSGGYEVPS--TVFSPKPTRDH----QQDVDEEQAAIVNQ--------P 219
                     :||.:::|.  |..||  ||...:...|.    .:::.|....:..|        .
  Rat  1295 LCSVPSSSPSVFSEMSSD--YAQPSATTVAEDEDKEDEFGYSWKNIQERYGTLTGQLHMIELEKG 1357

  Fly   220 YRTTPLVLPGAKVKKDAPTTESYLRHYPNPAVRAHPG--------------------HDYHDSIM 264
            :....|.|.|   .||......::............|                    |....||:
  Rat  1358 HSGLGLSLAG---NKDRTRMSVFIVGIDPTGAAGRDGRLQIADELLEINGQILYGRSHQNASSII 1419

  Fly   265 K----------QRVADTMLHKVV--GSEADTGRVFHKQFNSPIGLYSNNNIEDTIRSTVPFATSE 317
            |          .|.||.:....|  ||.||.   ......||    .|..:|       |..|:.
  Rat  1420 KCAPSKVKIIFIRNADAVNQMAVCPGSAADP---LPSTSESP----QNKEVE-------PSITTS 1470

  Fly   318 SNRLKDSPL----HRPLPTKLNGYKKTV-QYDPRNSETYRAIQEEGGYSNYGQSSPQEVTIPVQT 377
            ::.:..|.|    |..||....|....: :.|..|..|.:::.|.||.:..|:..|.:..:.|. 
  Rat  1471 ASAVDLSSLTNVYHLELPKDQGGLGIAICEEDTLNGVTIKSLTERGGAAKDGRLKPGDRILAVD- 1534

  Fly   378 KVYQPNRLVPG 388
                 :.||.|
  Rat  1535 -----DELVAG 1540

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Zasp66NP_729395.2 PDZ_signaling <68..115 CDD:238492 18/52 (35%)
DUF4749 285..359 CDD:292558 16/78 (21%)
MpdzXP_006238402.1 L27_2 6..63 CDD:117611
PDZ_signaling 140..222 CDD:238492
PDZ_signaling 256..335 CDD:238492
PDZ 374..463 CDD:214570
PDZ_signaling 552..621 CDD:238492
PDZ_signaling 693..776 CDD:238492
PDZ_signaling 993..1063 CDD:238492
PDZ_signaling 1150..1241 CDD:238492 29/108 (27%)
PDZ 1348..1433 CDD:214570 11/87 (13%)
PDZ_signaling 1482..1561 CDD:238492 16/65 (25%)
MPDZ_u10 1563..1624 CDD:293272
PDZ 1625..1709 CDD:214570
PDZ_signaling 1721..1801 CDD:238492
PDZ_signaling 1858..1943 CDD:238492
PDZ_signaling 1984..2067 CDD:238492
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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