DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and GSC2

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_005306.1	Gene:	GSC2 / 2928	HGNCID:	4613	Length:	205	Species:	Homo sapiens

Alignment Length:	82	Identity:	19/82 - (23%)
Similarity:	31/82 - (37%)	Gaps:	25/82 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 VPGYELP--TSYRPQPT-------PKPPLVPLPSPCR--------------RRSSSGLKKRVHFA 61
            :|...||  .:..|||.       |:.|..|..:||.              ..:::||..|:.:.
Human    29 LPERSLPARAACPPQPAGRQSPAKPEEPGAPEAAPCACCCCCGPRAAPCGPPEAAAGLGARLAWP 93

  Fly    62 DEQN--VGVQVGSPAHG 76
            ....  |.:.:|:||.|
Human    94 LRLGPAVPLSLGAPAGG 110

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	4/9 (44%)
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558
GSC2	NP_005306.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	33..58		7/24 (29%)
		Homeobox	129..182	CDD:278475
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	185..205
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.030