DRSC/TRiP Functional Genomics Resources

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Protein Alignment Zasp66 and Pdlim2

DIOPT Version :9

Sequence 1:NP_729395.2 Gene:Zasp66 / 38988 FlyBaseID:FBgn0035917 Length:430 Species:Drosophila melanogaster
Sequence 2:NP_001007623.1 Gene:Pdlim2 / 290354 RGDID:1359203 Length:349 Species:Rattus norvegicus


Alignment Length:404 Identity:79/404 - (19%)
Similarity:123/404 - (30%) Gaps:140/404 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 PSPCRRRSSSGLKKRVHFADEQNVGVQVGSPAHGELLRGDIISKIGEYDARDLSHADAQQLFRGA 107
            |:|...|.|.|  :..|.........:.|.....:|..||||..|....|..:.||:||...|.:
  Rat    10 PAPWGFRISGG--RDFHTPIIVTKVTERGKAEAADLRPGDIIVAINGESAESMLHAEAQSKIRQS 72

  Fly   108 GNEIRLVVHRDNKIAYTQGATQEAGPGSRSNSTLPPVTPDLMPHRGPSPFLPGPSHFERALQLPV 172
            .:.:||.:.|          :|.|.||                                      
  Rat    73 ASPLRLQLDR----------SQTASPG-------------------------------------- 89

  Fly   173 DTLPQTVFPQLNSSGGYEVPSTVFSPKPTRDHQQDVDEEQAAI------------VNQPYRTTPL 225
                     |:|..|..::.:|.|.......|.....:..|..            .:.|..|:|:
  Rat    90 ---------QINGEGSLDMLATRFQGSLRTHHNSQSSQRSACFSPASLSPRPDSPFSTPPPTSPI 145

  Fly   226 VLPGAKVKKDAPTTESYLRHYPNPAVRAH---PGHDYHDSIMKQRVADTMLHKVVGSEADTGRVF 287
            .|.|..|   ...:...|.|.|..|...|   ||............:|:.:..::.|   .||. 
  Rat   146 ALSGENV---IGCSFQSLTHSPGLAATHHLTYPGQPTSQQAGHSSPSDSTVRVLLHS---PGRP- 203

  Fly   288 HKQFNSPIGLYSNNNIEDTIRSTVPFATSESNRLKDSPLHRPLPTKLNGYKKTVQYDPRNSETYR 352
                :||  ..|:.::|:                 ||.:.:.|.....|     :..||.|.::|
  Rat   204 ----SSP--RLSSLDLEE-----------------DSEVFKMLQENRQG-----RAAPRQSSSFR 240

  Fly   353 AIQ------EEGGYSNYGQSSPQEVTIPVQTKVYQPNRLVP-GKKPVSAPVSRPP------YNVV 404
            .:|      |.||                 |..:.|:.|.| ...|.|..::.||      ...|
  Rat   241 LLQEALEAEERGG-----------------TPAFVPSSLSPKASLPTSRALATPPKLHTCEKCSV 288

  Fly   405 NTHDENIR-QSGSF 417
            |..::.:| |.|.:
  Rat   289 NISNQAVRIQEGRY 302

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Zasp66NP_729395.2 PDZ_signaling <68..115 CDD:238492 15/46 (33%)
DUF4749 285..359 CDD:292558 15/79 (19%)
Pdlim2NP_001007623.1 PDZ_signaling 9..80 CDD:238492 21/71 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 72..95 9/79 (11%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 108..147 5/38 (13%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 168..212 10/53 (19%)
DUF4749 <190..252 CDD:292558 18/93 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 250..272 8/38 (21%)
LIM_Mystique 283..335 CDD:188833 5/20 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 71 1.000 Inparanoid score I5207
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24214
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.150

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