DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and Pdlim7

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	XP_038951356.1	Gene:	Pdlim7 / 286908	RGDID:	628769	Length:	464	Species:	Rattus norvegicus

Alignment Length:	246	Identity:	54/246 - (21%)
Similarity:	85/246 - (34%)	Gaps:	64/246 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 PSPCRRRSSSGLKKRVHFADEQNVGVQV------GSPAHGELLRGDIISKIGEYDARDLSHADAQ 101
            |:|...|...|        .:.||.:.:      |..|...:..||.:..|...:|..|:|.:||
  Rat    11 PAPWGFRLQGG--------KDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIEAQ 67

  Fly   102 QLFRGAGNEIRLVVHRDNKIAYTQGATQEA------------GPGSRSNST-----LPPVTPDLM 149
            ...|..|..:.|.:.|...   .|...|:|            .|.:..|.|     .||.|...:
  Rat    68 NKIRACGERLSLGLSRAQP---AQSKPQKALTPPADPPRYTFAPSASLNKTARPFGAPPPTDSAL 129

  Fly   150 PHRGPSP---------FLPGPSHFERALQLPVDTLPQTVFPQLNSSGGYEVPSTVFSPKPTRDHQ 205
            ...|..|         .:|..|. :|.::...|..|:   |....|..:.:.:.:..    .:..
  Rat   130 SQNGCRPLTSQQLLRQLVPDASK-QRLMENTEDWRPR---PGTGQSRSFRILAHLTG----TEFM 186

  Fly   206 QDVDEEQAAIVNQPYRT-TPLVLPGAKVKKDA---PTTESYLRHYPNPAVR 252
            ||.|||.....:|..|| .|  .|.:.:.:::   |||       |:|..|
  Rat   187 QDPDEEFMKKSSQVPRTEAP--APASTIPQESWPGPTT-------PSPTSR 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	13/52 (25%)
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558
Pdlim7	XP_038951356.1	PDZ_signaling	5..79	CDD:238492	18/75 (24%)
		PHA03247	<11..261	CDD:223021	54/246 (22%)
		DUF4749	<163..192	CDD:406377	6/35 (17%)
		LIM1_Enigma	289..340	CDD:188836
		LIM2_Enigma	348..399	CDD:188840
		LIM3_Enigma	407..461	CDD:188842
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	71	1.000	Inparanoid score	I5207
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24214
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.150