Protein Alignment Zasp66 and WHRN

DIOPT Version :9

• Sequence 1: NP_729395.2
• Gene: Zasp66 / 38988
• FlyBaseID: FBgn0035917
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: XP_011516787.1
• Gene: WHRN / 25861
• HGNCID: 16361
• Length: 918
• Species: Homo sapiens
• Alignment Length: 493
• Identity: 100/493 - (20%)
• Similarity: 149/493 - (30%)
• Gaps: 179/493 - (36%)

  Fly    13 SRPAFWKVPGYELPTSYRPQPTPKPPLVPLPSPCRRRSSSGLKKRV-------HFADEQ------ 64
            ::|.|:|.|.....|                     .||.|.:.||       |..:||
Human   400 NKPGFYKGPAGSQVT---------------------LSSLGNQTRVLLEEQARHLLNEQEHATMA 443

  Fly    65 ---------NVGVQVGSPAHGELL----RGDIISKI-GEYDARDLSHADAQQLFR---------- 105
                     :|.|:....|..:||    :..::|:: |....:||...|...|.|
Human   444 YYLDEYRGGSVSVEALVMALFKLLNTHAKFSLLSEVRGTISPQDLERFDHLVLRREIESMKARQP 508

  Fly   106 ---GAGNEIRLVVHRDNKIAYTQGAT------------------------QEAGPGSRSN-STLP 142
               |||:...:|.:.|...:.....|                        :|.|...:.| :.||
Human   509 PGPGAGDTYSMVSYSDTGSSTGSHGTSTTVSSARERLLWLIDLMENTLDLEETGEAVQGNINALP 573

  Fly   143 PVTPD--LMPHRGPSPF--LPGPSHFERALQLPV---------DTLPQTVFPQLNSSGGYEVPST 194
            .|:.|  ....:|.|.|  ||.|....:...||:         |..|.:..|  :.||      |
Human   574 DVSVDDVRSTSQGLSSFKPLPRPPPLAQGNDLPLGQPRKLGREDLQPPSSMP--SCSG------T 630

  Fly   195 VFSPKPTRDHQQDVDEEQAAIVNQPYRTTPLVLPGAKVKKDAPTTESYLRHYP-NPAVRAHPGHD 258
            |||....|              :.|..|.|  .||....:|.|::..|....| ||:.: .| .|
Human   631 VFSAPQNR--------------SPPAGTAP--TPGTSSAQDLPSSPIYASVSPANPSSK-RP-LD 677

  Fly   259 YHDSIMKQRVADTMLHKVVGSEADTGRVFHKQFNSPIGLYSNNNIEDTIRSTVPFATSESN-RLK 322
            .|.:::.|.                          |||.:........::|....||.... .|.
Human   678 AHLALVNQH--------------------------PIGPFPRVQSPPHLKSPSAEATVAGGCLLP 716

  Fly   323 DSPLHRPLPTKLNGYKKTVQYDPRNSE----TYRAIQEEGGYSNYGQSSPQ-------------- 369
            .||...|..|..|.:...|:....:||    ..||:.:....|...|.|..
Human   717 PSPSGHPDQTGTNQHFVMVEVHRPDSEPDVNEVRALPQTRTASTLSQLSDSGQTLSEDSGVDAGE 781

  Fly   370 -EVTIP------VQTKVYQPNRLVPGKKPVSAPVSRPP 400
             |.:.|      |.||......|...::|... .::||
Human   782 AEASAPGRGRQSVSTKSRSSKELPRNERPTDG-ANKPP 818

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	14/64 (22%)
		DUF4749	285..359	CDD:292558	17/78 (22%)
WHRN	XP_011516787.1	HN_L-whirlin_R1_like	37..112	CDD:259822
		PDZ_signaling	138..215	CDD:238492
		PDZ_signaling	277..357	CDD:238492
		HN_L-whirlin_R2_like	419..499	CDD:259823	17/79 (22%)
		PDZ_signaling	827..898	CDD:238492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900