DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and pxl1

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_596112.1	Gene:	pxl1 / 2540856	PomBaseID:	SPBC4F6.12	Length:	438	Species:	Schizosaccharomyces pombe

Alignment Length:	271	Identity:	51/271 - (18%)
Similarity:	88/271 - (32%)	Gaps:	89/271 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 PTPKPPLVPLPSPCRRRSSSGLKKRVHF--ADEQNVGVQVGSPAHGELLRGDIISKIGEYDARDL 95
            |.|:|.|....||..:|:.:..:.||.|  .|::.....|.||
pombe    56 PLPQPSLKTPESPLSKRNPTIKQNRVRFDLPDDELSRSNVSSP---------------------- 98

  Fly    96 SHADAQQLFRGAGNEIRLVVHRDNKIAYTQGATQEAGPGSRSNSTLPPVTPDLMPHRGPSPFLPG 160
                                   .|...|          |.|.||...:..:|:|.      ||.
pombe    99 -----------------------EKTLLT----------SASTSTFDSLKKELLPE------LPS 124

  Fly   161 PSHFERALQLPVDTLPQTVFPQLNSSGGYEVPSTVF----SPKPTRDHQQDVDEEQAAIVNQPYR 221
            .::.:.      |..|.:. .:|||...|.....|:    ..:|..|| ..:::.|....::...
pombe   125 LAYSDD------DEFPSSP-EELNSHVNYPDVRNVYDCHTGLQPLVDH-DCIEDRQKTFASKQLP 181

  Fly   222 TTPLVLPGAKVKKDAPTTESYLRH-------YPNPAVRAH-PGHDYHDSIMKQRVADTMLHKVVG 278
            |.|| ...:|:....|...|:  |       ||.|...:. |.:...:::.:   :|::...:|.
pombe   182 TLPL-QKSSKLSNRRPALHSF--HSAPANSLYPLPTPTSQLPSNLSSNNLFQ---SDSLKPSMVS 240

  Fly   279 SEADTGRVFHK 289
            |...|..|.::
pombe   241 SHTSTKPVLYR 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	3/46 (7%)
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558	1/5 (20%)
pxl1	NP_596112.1	LIM	258..314	CDD:278823
		LIM	318..370	CDD:259829
		LIM	378..428	CDD:259829
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030