DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and Pdlim4

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_001380800.1	Gene:	Pdlim4 / 24915	RGDID:	3575	Length:	335	Species:	Rattus norvegicus

Alignment Length:	243	Identity:	55/243 - (22%)
Similarity:	80/243 - (32%)	Gaps:	81/243 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 PSPCRRRSSSGLK-------KRVHFADEQNVGVQVGSPAH-GELLRGDIISKIGEYDARDLSHAD 99
            |||...|...|..       .|||          .||.|. ..|..||:|..|.......::|.:
  Rat    10 PSPWGFRLVGGRDFSAPLTISRVH----------AGSKAALAALCPGDLIQAINGESTELMTHLE 64

  Fly   100 AQQLFRGAGNEIRLVVHR----------DNKIAYTQ---------GATQEAGPGSRSNSTLPPVT 145
            ||...:|..:.:.|.|.|          |:|....:         ...|:..|.:...|::..::
  Rat    65 AQNRIKGCHDHLTLSVSRPENKNWPSSPDDKAQAHRIHIDPEAQASLLQDGSPATSRRSSISGIS 129

  Fly   146 PDLMPHRG--PSPFLPGPSHFERALQLPVDTLPQTVFPQLNSSGGYEVPSTV----FSPKPTRDH 204
              |..:|.  .||:...|       :|||        |...||....:||.:    .||.|:.|
  Rat   130 --LEDNRSGLGSPYGQPP-------RLPV--------PHNGSSNEVTLPSQMSALHVSPPPSAD- 176

  Fly   205 QQDVDEEQAAIVNQPYRTTPLVLPGAKVKKDAPTTESY--LRHYPNPA 250
                              ||.:||..:..:....:|.|  ||....||
  Rat   177 ------------------TPRILPRNRDCRVDLGSEVYRMLREPAEPA 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	13/47 (28%)
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558
Pdlim4	NP_001380800.1	PDZ_signaling	2..80	CDD:238492	21/79 (27%)
		DUF4749	139..235	CDD:406377	25/102 (25%)
		LIM_RIL	260..312	CDD:188835
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	71	1.000	Inparanoid score	I5207
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24214
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.150