Protein Alignment Zasp66 and Cytip

DIOPT Version :9

• Sequence 1: NP_729395.2
• Gene: Zasp66 / 38988
• FlyBaseID: FBgn0035917
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_631939.1
• Gene: Cytip / 227929
• MGIID: 2183535
• Length: 359
• Species: Mus musculus
• Alignment Length: 406
• Identity: 78/406 - (19%)
• Similarity: 132/406 - (32%)
• Gaps: 158/406 - (38%)

  Fly     1 MTTSRSSASASFSRPAFW---KVP----------GYELPTSYRPQPTPKPPLVPLPSPCRRRSSS 52
            :..:|||:...||    |   ||.          |:|:.| ||.|
Mouse    59 LALARSSSLGDFS----WSQRKVVTVEKQDNGTFGFEIQT-YRLQ-------------------- 98

  Fly    53 GLKKRVHFADEQNV----------GVQVGSPAH-GELLRGDIISKIGEYDARDLSHADAQQLFRG 106
                      .||:          .||..|||| ..|..|||.:.:........:|.....|.|.
Mouse    99 ----------NQNICSSEVCTMICKVQEDSPAHCAGLQVGDIFANVNGVSTEGFTHKQVVDLIRS 153

  Fly   107 AGNEIRLVVHRDNKIAYTQGATQEAGPGSRSNSTLPPVTPDLMPHRGPSPFLPGPSHFERA-LQL 170
            :||.:.:                     ...|.|        |.||             || |:.
Mouse   154 SGNLLTI---------------------ETLNGT--------MIHR-------------RAELEA 176

  Fly   171 PVDTLPQTV---FPQLNSSGGYEV----PSTVFSPKPTRDHQQDVDEEQAAIVNQPYRTTPLVLP 228
            .:.||.||:   :.:|.|....|.    ..|..||     :.:::|.:::::.......:|.:|.
Mouse   177 KLQTLKQTLKKKWVELRSLHLQEQRLLHGDTANSP-----NLENMDLDESSLFGNLLGPSPALLD 236

  Fly   229 GAKVKKDAPTTESYLRHYPNPAVRAHPGHDYHDSIMKQRVADTMLHKVVGSEADTGRVFHKQFNS 293
            ..::..:: :.:|:|   .:..|.:..|  |..|:               ||......|.:|.::
Mouse   237 RHRLSSES-SCKSWL---SSLTVDSEDG--YRSSM---------------SEDSIRGAFSRQTST 280

  Fly   294 PIGLYSNNNIEDTIRSTVPFATSESNR---LKDSPLHRPLPTKLNGYKKTVQYDPRNSE------ 349
            ....:.:.:.::.:|:    |:|..||   :..|....||..  :.|.......||.|.
Mouse   281 DDECFHSKDGDEILRN----ASSRRNRSISVTSSGSFSPLWE--SNYSSVFGTLPRKSRRGSVRK 339

  Fly   350 --------TYRAIQEE 357
                    .:||::||
Mouse   340 QILKFIPGLHRAVEEE 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	15/47 (32%)
		DUF4749	285..359	CDD:292558	18/90 (20%)
Cytip	NP_631939.1	PDZ_signaling	76..161	CDD:238492	25/136 (18%)
		Interaction with CYTH1. /evidence=ECO:0000250	166..188		11/42 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900