Protein Alignment Zasp66 and Pax6

DIOPT Version :9

• Sequence 1: NP_729395.2
• Gene: Zasp66 / 38988
• FlyBaseID: FBgn0035917
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_001231127.1
• Gene: Pax6 / 18508
• MGIID: 97490
• Length: 436
• Species: Mus musculus
• Alignment Length: 455
• Identity: 87/455 - (19%)
• Similarity: 149/455 - (32%)
• Gaps: 155/455 - (34%)

  Fly    59 HFADEQNVGVQVGSPAHGELLRGDIISKIGEYDAR--DLS-----HADAQQLFRGAGNEIRLVVH 116
            |....|..||.|......:..|..|: ::....||  |:|     ||||:            |..
Mouse     5 HSGVNQLGGVFVNGRPLPDSTRQKIV-ELAHSGARPCDISRILQTHADAK------------VQV 56

  Fly   117 RDNK------IAYTQGATQEAGP-------GSRSNSTLPPVTPDLMPHRGPSPFLPGPSHFERAL 168
            .||:      ::...|...|.|.       ||:.....|.|...:..::...|.:......:|.|
Mouse    57 LDNENVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLL 121

  Fly   169 QLPV---DTLPQ------------TVFPQLNSSGGYE------------------VPSTVFSPKP 200
            ...|   |.:|.            :...|:.:.|.|:                  .|.|....:|
Mouse   122 SEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQP 186

  Fly   201 TRD-----------------HQQDVDEEQAAI----VNQPYRTTPLVLPGAKVKKDAPTTESYLR 244
            |:|                 :.:|.||.|..:    ..|..||:     ..:.:.:|...|....
Mouse   187 TQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTS-----FTQEQIEALEKEFERT 246

  Fly   245 HYPN-------------PAVRAHPGHD-------YHDSIMKQR--VADTMLHKVVGSEADTGRVF 287
            |||:             |..|......       ..:.:..||  .::|..|..:.|...|. |:
Mouse   247 HYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTS-VY 310

  Fly   288 H--KQFNSPIGLYSNNNI----EDTIRST------VPFATSESNRLKDSPLHRPLPTKLNGY--- 337
            .  .|..:|:..:::.::    :..:.:|      :|..|..:|    .|:..|:|::.:.|
Mouse   311 QPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANN----LPMQPPVPSQTSSYSCM 371

  Fly   338 ---------KKTVQYDPRNSETYRAIQEEG--GYSNYGQSSPQEVTIPVQTKVYQPNRLVPGKKP 391
                     :....|.|.:.:|:...|..|  |.::.|..|| .|::|||         |||.:|
Mouse   372 LPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISP-GVSVPVQ---------VPGSEP 426

  Fly   392  391
            Mouse   427  426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	12/53 (23%)
		DUF4749	285..359	CDD:292558	16/99 (16%)
Pax6	NP_001231127.1	PAX	4..142	CDD:128645	31/149 (21%)
		Homeobox	228..281	CDD:395001	9/57 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030