DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and T19B10.5

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_505852.3	Gene:	T19B10.5 / 179553	WormBaseID:	WBGene00011833	Length:	596	Species:	Caenorhabditis elegans

Alignment Length:	226	Identity:	50/226 - (22%)
Similarity:	79/226 - (34%)	Gaps:	69/226 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   226 VLPGAKVK-----------KDAPTTESYLRHYPNPAVRAHPGHDYHDSIMKQRVADTMLHKVVGS 279
            :|.|.|:|           :||.|..||...|   .|:..         ::::::|:.  .|..|
Worm   168 ILVGDKIKSLTINFENMVYEDAVTLLSYSSPY---KVKLE---------LERKLSDSA--SVSDS 218

  Fly   280 EADTGRVFHKQFNSPIGLYSNNNIEDTIRSTVPFATSESN-RLKDSPLHRPLPTKLNGYKKTVQY 343
            :.|....:|..|.|....:.:.|...||.:....||:... ...||.....||.:    ::.::.
Worm   219 DDDKEMRYHPLFRSNTLTHVHFNPLGTISTPTSIATTPQRCTSTDSKQKHALPPQ----REIIEP 279

  Fly   344 DPR-----NSETYRAIQEEGGYSNYGQ-------------------SSPQEVTIPVQTKVYQP-- 382
            |..     ||:...|.......|:||.                   |...|||..:..||..|
Worm   280 DSTTCADDNSQARDADNSRMDSSDYGSDGISDCRESTASDGTQKTLSDRIEVTDIIFDKVKSPTP 344

  Fly   383 ---------NRLVP-GKKPVS---APVSRPP 400
                     ..|.| .:|.||   :||::||
Worm   345 PPLRKLEQCTELPPKPRKMVSRSPSPVNKPP 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558	16/79 (20%)
T19B10.5	NP_505852.3	PDZ	137..208	CDD:214570	11/51 (22%)
T19B10.5	NP_505852.3	PTZ00449	<340..483	CDD:185628	10/36 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900