DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and Gsc

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_034481.1	Gene:	Gsc / 14836	MGIID:	95841	Length:	256	Species:	Mus musculus

Alignment Length:	164	Identity:	37/164 - (22%)
Similarity:	54/164 - (32%)	Gaps:	30/164 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 PA-HGELL---RGDIISKIGEYDARDLSHADAQQLFRGAGNEIRLVVHR--DNKIAYTQGATQEA 131
            || ||:.|   .|...|..|.:..|.::..       |||....:...|  .|...|.|...|.|
Mouse    36 PALHGDSLYGAGGGTSSDYGAFYPRPVAPG-------GAGLPAAVGSSRLGYNSYFYGQLHVQAA 93

  Fly   132 GPGSRSNSTLPPV-------TPDLMPHRGPSPFLPGPSHFERALQLPVDTLPQTVFPQLNSSGGY 189
            ..|......:||:       .|....:.||...|..|...:....:.|.||.:|....||.
Mouse    94 PVGPACCGAVPPLGAQQCSCVPTPPGYEGPGSVLVSPVPHQMLPYMNVGTLSRTELQLLNQ---- 154

  Fly   190 EVPSTVFSPKPTRDHQQDVDEEQAAIVNQPYRTT 223
                  ...:..|.|:....:||...:...::.|
Mouse   155 ------LHCRRKRRHRTIFTDEQLEALENLFQET 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	12/45 (27%)
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558
Gsc	NP_034481.1	Homeobox	163..216	CDD:278475	4/20 (20%)
Gsc	NP_034481.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	213..256
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030