DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and dmbx1a

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_694509.1	Gene:	dmbx1a / 142987	ZFINID:	ZDB-GENE-020117-1	Length:	388	Species:	Danio rerio

Alignment Length:	182	Identity:	41/182 - (22%)
Similarity:	59/182 - (32%)	Gaps:	66/182 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 PGYELPTSYRPQPTPKPPLVPLPSPCRRRSSSGLKKRVHFADEQNVGVQVGSPAHGELLRGDIIS 85
            ||...|...|..|.|..   ||.||....||||:               .|.           ||
Zfish   235 PGNLSPLCKRLSPKPDS---PLGSPAISSSSSGV---------------TGG-----------IS 270

  Fly    86 KIGEYDARDLSHADAQQLFRGAGNEIRLVVHRDNKIAYTQGATQEAGPGSRSNSTLPPVTPDLMP 150
            :...|.:..||....|:.||      :.:...:|.:.|               .:....||..:|
Zfish   271 QSHSYSSSPLSLFRLQEQFR------QHMAATNNLVHY---------------PSFDMATPSSIP 314

  Fly   151 HRGPSPFLPGPSHFERALQLPVDTLPQTV---------FPQLNSSGGYEVPS 193
            :.|.:..:|.|..     .||..:..|::         .|.|.:|||  :||
Zfish   315 YLGMNVNMPAPLG-----SLPCQSYYQSLSHHAQQVWNSPLLQASGG--LPS 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	9/46 (20%)
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558
dmbx1a	NP_694509.1	Homeobox	74..127	CDD:278475
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	129..272		17/65 (26%)
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	365..378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030