DRSC/TRiP Functional Genomics Resources

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Protein Alignment Zasp66 and Patj

DIOPT Version :9

Sequence 1:NP_729395.2 Gene:Zasp66 / 38988 FlyBaseID:FBgn0035917 Length:430 Species:Drosophila melanogaster
Sequence 2:NP_766284.2 Gene:Patj / 12695 MGIID:1277960 Length:1834 Species:Mus musculus


Alignment Length:443 Identity:88/443 - (19%)
Similarity:137/443 - (30%) Gaps:140/443 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    31 PQPTPKPPLVPLPSPC-------------RRRSSSGLK-----------KRVHFADEQNVGVQVG 71
            |.|....||...|:.|             :.||..||.           ..:|...|:....:  
Mouse  1448 PLPVDPAPLSVDPATCPIVPGQEMIIEISKGRSGLGLSIVGGKDTPLDAIVIHEVYEEGAAAR-- 1510

  Fly    72 SPAHGELLRGDIISKIGEYDARDLSHADAQQLFRGAGNEIRLVVHRDNKIAYTQGATQEAGPGSR 136
               .|.|..||.|.::...|.|..||.:|....|....::||||:|| :..|            |
Mouse  1511 ---DGRLWAGDQILEVNGVDLRSSSHEEAITALRQTPQKVRLVVYRD-EAQY------------R 1559

  Fly   137 SNSTLPPVTPDLMPHRGPSPFLPGPSHFERALQLPVDTLPQTVFPQLNSSGGYEVPSTVFSPKPT 201
            ....|.....||....|            |.|.|       ::..:.:.||       ||.....
Mouse  1560 DEENLEVFLVDLQKKTG------------RGLGL-------SIVGKRSGSG-------VFISDIV 1598

  Fly   202 RDHQQDVDEEQAAIVNQPYRTTPLVLPGAKVKKDAPTTESYLRHYPNPAVRAHPGHDYHDSIMKQ 266
            :....|:|                   |..::.|              .:.:..|.|...:  .|
Mouse  1599 KGGAADLD-------------------GRLIRGD--------------QILSVNGEDMRHA--SQ 1628

  Fly   267 RVADTMLHKVVG-SEADTGRV-------FHKQFNSPIGLYSNNNIEDTIR-STVPFATSESN--- 319
            ....|:|..|.| .:.:.||:       ..|...:..|  ..::...:.| |..|..||..|   
Mouse  1629 ETVATILKCVQGLVQLEIGRLRAGSWAASRKTSQNSQG--DQHSAHSSCRPSFAPVITSLQNLVG 1691

  Fly   320 --RLKDSPLHRPLPTKLNGYKKTVQYDPRNSETYRAIQEEGGYSNYGQSSPQEVTIPVQTKVYQP 382
              |..|.|            :|..:.:||..|..|.:.:..|.|..|........||:...:.|.
Mouse  1692 TKRSSDPP------------QKCTEEEPRTVEIIRELSDALGISIAGGKGSPLGDIPIFIAMIQA 1744

  Fly   383 N-------RLVPGKKPVSAPVSRPPYNVVNTHDENIRQSGSFNRLMYSVIGAT 428
            |       :|..|.:.||  ::..|.:.::..|.......:|.|::..|:..|
Mouse  1745 NGVAARTQKLKVGDRIVS--INGQPLDGLSHTDAVNLLKNAFGRIILQVVADT 1795

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Zasp66NP_729395.2 PDZ_signaling <68..115 CDD:238492 13/46 (28%)
DUF4749 285..359 CDD:292558 17/86 (20%)
PatjNP_766284.2 L27_2 8..65 CDD:312549
PDZ_signaling 135..218 CDD:238492
PDZ_signaling 248..325 CDD:238492
PDZ_signaling 363..450 CDD:238492
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 456..488
PDZ_signaling 572..636 CDD:238492
PDZ 685..774 CDD:214570
PDZ_signaling 1072..1163 CDD:238492
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1171..1219
PDZ 1242..1327 CDD:214570
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1340..1453 2/4 (50%)
MPDZ_u10 <1453..1468 CDD:374710 4/14 (29%)
PDZ 1469..1554 CDD:214570 21/89 (24%)
PDZ_signaling 1566..1646 CDD:238492 21/140 (15%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1657..1676 2/20 (10%)
PDZ_signaling 1707..1792 CDD:238492 19/86 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1811..1834
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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