DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and cytip

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	XP_003199223.2	Gene:	cytip / 100537036	ZFINID:	ZDB-GENE-140106-76	Length:	343	Species:	Danio rerio

Alignment Length:	212	Identity:	48/212 - (22%)
Similarity:	70/212 - (33%)	Gaps:	75/212 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 VQVGSPAH-GELLRGDIISKIGEYDARDLSHADAQQLFRGAGNEIRL------VVHR---DNKIA 122
            ||.||.|. ..|..||||..:........:|.:..:|.|.:.|.::|      |:.|   :.|:.
Zfish   115 VQDGSAAETAGLTAGDIILSVNGVSIEGSTHQNIIELIRESSNTLKLETVSGSVMKRIELEKKMH 179

  Fly   123 Y----------------------TQGATQEAG-----------------PGSR--SNSTLPPVTP 146
            |                      |||...|:.                 .|.|  |:|:...:..
Zfish   180 YLKQTLREKWVELQSLTLKEKRLTQGNLNESAQYLSVDSVMSLSSPMGRSGQRFSSDSSCRSIMT 244

  Fly   147 D----------LMPHRGP-SPFLPGPSHFERALQLPVDTL-PQTVFPQLNSSG-------GYEV- 191
            |          :.....| ||.....|.|    ||.|..| |.|....::.:|       |:|.
Zfish   245 DDSEDGAFMSSVFDDSSPLSPIESSGSFF----QLEVGALRPITRTRSISLTGSNSSLSPGWETS 305

  Fly   192 PSTVFSPKPTRDHQQDV 208
            ||::|...|.|..:..|
Zfish   306 PSSLFGTLPRRSRKGSV 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	15/53 (28%)
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558
cytip	XP_003199223.2	PDZ_signaling	78..162	CDD:238492	14/46 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900