DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp66 and whrna

DIOPT Version :9

Sequence 1:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	XP_002665968.3	Gene:	whrna / 100334777	ZFINID:	ZDB-GENE-091118-27	Length:	939	Species:	Danio rerio

Alignment Length:	223	Identity:	58/223 - (26%)
Similarity:	87/223 - (39%)	Gaps:	69/223 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LPTSYRPQPTPKPPLVPLPSPCRRRSSSGLKKRVHFADEQNVGVQV-----GSPAHGELLR-GDI 83
            |..::.|:|..:...|.|.   |.:|:.||...:....|..||:.|     ||.|..|.|| ||.
Zfish   162 LGRNFLPEPPGEIRQVILK---RHKSNEGLGFSIRGGSEHGVGIYVSLVEPGSLAEKEGLRMGDQ 223

  Fly    84 ISKIGEYDARDLSHADAQQLFRGAGNEIRLVVHRDNKI--------AYTQGATQEAGPGSRSNST 140
            |.|:.:.....::||||.::.:|: .::.:.|....:|        .||.     ..|..||.|
Zfish   224 IMKVNDKVFDRVTHADAVKVLKGS-KKLCMSVRSVGRIPGGYITNHVYTW-----VDPQGRSVS- 281

  Fly   141 LPPVTPDLM-PHRGPSPFLPGPSHFERALQLPVDTLPQTVFPQLNSSGGYEVPSTVFSPKPTRDH 204
             ||  |||: .||..                   ||.::     ||.|              |.|
Zfish   282 -PP--PDLLAEHRSA-------------------TLRRS-----NSQG--------------RSH 305

  Fly   205 Q---QDVDEEQAAIVNQPYRTTPLVLPG 229
            .   ||.||::..:|....|:..|::.|
Zfish   306 MQLLQDGDEKKVNLVLDDGRSLGLMIRG 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	16/52 (31%)
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558
whrna	XP_002665968.3	HN_L-whirlin_R1_like	25..102	CDD:259822
		PDZ_signaling	174..255	CDD:238492	25/84 (30%)
		PDZ_signaling	314..394	CDD:238492	5/20 (25%)
		HN_L-whirlin_R2_like	459..538	CDD:259823
		PDZ_signaling	848..919	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900