DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment GAPsec and SGSM2

DIOPT Version :9

Sequence 1:NP_648245.2 Gene:GAPsec / 38987 FlyBaseID:FBgn0035916 Length:403 Species:Drosophila melanogaster
Sequence 2:XP_011522403.1 Gene:SGSM2 / 9905 HGNCID:29026 Length:1103 Species:Homo sapiens


Alignment Length:316 Identity:68/316 - (21%)
Similarity:119/316 - (37%) Gaps:68/316 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    85 SSNRASVDGGDGDKVDSG-GVGLQD-----HPLSEGPESAWNTFFNDNEFLLQIDKDVRRLCPDI 143
            ||...||..|....:|.| .||.::     ...|.||..|.:|                      
Human   800 SSRNYSVASGIQSSLDEGQSVGFEEEDGGGEEGSSGPGPAAHT---------------------- 842

  Fly   144 SFFQQPTDYPCEIVVHSKGEHGRRLHERVVPAVLSSANVERKGLGMTKINLITKRSVENYAAMEE 208
              .::|.|...|.....:.|.|..| ..|..|..:...::...|.:.:|:...:|...||     
Human   843 --LREPQDPSQEKPQAGELEAGEEL-AAVCAAAYTIELLDTVALNLHRIDKDVQRCDRNY----- 899

  Fly   209 GQEAHW-------EVVQRILFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDLTYRAHAEADCFF 266
                 |       |.::.::..|...:...||||||.:::.|:...:.:| .|.|.         
Human   900 -----WYFTPPNLERLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTLDND-QLAYS--------- 949

  Fly   267 CFTALMSEIRDFFIKTLDDAEGGIKFMMARLSNMLKSKDLSIYELLRSQELHPQ-YYSFRWLTLL 330
            ||:.||..:...|     ...|.:....|.:.::::..|..::||:.....:.. |:.:||..|.
Human   950 CFSHLMKRMSQNF-----PNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLD 1009

  Fly   331 LSQEFPLPDVLRIWDSVFADE--QRFDFLIKICCSMILIQREAILEN--DFASNVK 382
            ..:|....||..:|:.::|..  ....|::.|..:::...||.|.:|  ||...:|
Human  1010 FKRELLYEDVFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIK 1065

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GAPsecNP_648245.2 TBC <191..373 CDD:214540 40/191 (21%)
SGSM2XP_011522403.1 RUN 90..235 CDD:280855
PH_RUTBC 302..470 CDD:275431
TBC <885..1053 CDD:214540 40/192 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5210
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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