DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GAPsec and Usp6nl

DIOPT Version :9

Sequence 1:	NP_648245.2	Gene:	GAPsec / 38987	FlyBaseID:	FBgn0035916	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_852064.2	Gene:	Usp6nl / 98910	MGIID:	2138893	Length:	842	Species:	Mus musculus

Alignment Length:	376	Identity:	67/376 - (17%)
Similarity:	128/376 - (34%)	Gaps:	97/376 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 QFIEELVLPPGHSSNRASVDGGDGD----------------KVDSGGVGLQDHPLSEGPESAWNT 121
            |.::|||.|   |..:|:....|.|                |.|.|..|.:..|..:.....:..
Mouse     6 QLVKELVTP---SRQKAATAKEDSDQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVYKV 67

  Fly   122 -----FFNDNEFLL-------QIDKDVRRLCPDISFFQQPTDYPCEIVVHSKGEHGRRLHERV-- 172
                 |.::.|...       |...::.|....:...::...|          ::..:.|.|:
Mouse    68 TDRFGFLHEEELPYHNAAADRQKQLEIERTSKWLKMLKKWERY----------KNTEKFHRRIYK 122

  Fly   173 -VPAVLSS--------------------ANVERKGLG----MTKINLITKRSVENYAAMEEGQEA 212
             :|..|..                    :.::.:..|    :.:|:|...|:..::....:....
Mouse   123 GIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGV 187

  Fly   213 HWEVVQRILFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDLTYRAHAEADCFFCFTALMS---- 273
            ..:.:..:|..|:..|...||.|||::|...:...|           .|.|.|:....|.|
Mouse   188 KQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYM-----------NEEDAFWALVKLFSGPKH 241

  Fly   274 EIRDFFI----KTLDDAEGGIKFMMARLSNMLKSKDLSIYELLRSQELHPQYYSFRWLTLLLSQE 334
            .:..||:    |.|...|...|.:...||.:.:..|        |||::..:|:.:|........
Mouse   242 AMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLD--------SQEIYTSFYTMKWFFQCFLDR 298

  Fly   335 FPLPDVLRIWDSVFADEQRFDFLIKICCSMILIQREAILENDFASNVKLLQ 385
            .|....|||||....:.:|  .|..:..:::.:.::.:::......|:.||
Mouse   299 TPFRLNLRIWDIYIFEGER--VLTAMSYTILKLHKKHLMKLSMEELVEFLQ 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	40/189 (21%)
Usp6nl	NP_852064.2	TBC	120..335	CDD:214540	43/235 (18%)
Usp6nl	NP_852064.2	SPRR2	<590..642	CDD:291486
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810