DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GAPsec and Sgsm2

DIOPT Version :9

Sequence 1:	NP_648245.2	Gene:	GAPsec / 38987	FlyBaseID:	FBgn0035916	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001361617.1	Gene:	Sgsm2 / 97761	MGIID:	2144695	Length:	1050	Species:	Mus musculus

Alignment Length:	390	Identity:	88/390 - (22%)
Similarity:	147/390 - (37%)	Gaps:	105/390 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 AGPQDLIDLKQLRKLAFN-GVPDVQSFRALSWKLLLGYLGPRRSSWTTTLAQKRALYKQFIE--- 76
            :|||||.|.|..|:.... |.|.:                             .|..:|.:|
Mouse   711 SGPQDLEDSKPKREQEPGAGTPGI-----------------------------AAAEQQSVEFDS 746

  Fly    77 -ELVLPPGHSSNRASVDGGDGDKVDSG-GVGLQDHPL----SEGPESAWNTFFNDNEFLLQIDKD 135
             :..||   ||...||..|....:|.. .||.:|...    ||||.:|.:||...:      |..
Mouse   747 PDSGLP---SSRNYSVASGIQSSLDEAQSVGFEDDGAGEDGSEGPATAAHTFPGPH------DPG 802

  Fly   136 VRRLCPDISFFQQPTDYPCEIVVHSKGEHGRRLHERVVPAVLSSANVERKGLGMTKINLITKRSV 200
            ...|.|                 .|:.|.|:.| ..|..|..:...::...|.:.:|:...:|..
Mouse   803 QETLAP-----------------ASELEAGQEL-AAVCAAAYTIELLDTVALNLHRIDKDVQRCD 849

  Fly   201 ENYAAMEEGQEAHW-------EVVQRILFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDLTYRA 258
            .||          |       |.::.|:..|...:...||||||.:::.|:..::.:| .|.|.
Mouse   850 RNY----------WYFTTSNLERLRDIMCSYVWEHLDMGYVQGMCDLLAPLLVILDND-QLAYS- 902

  Fly   259 HAEADCFFCFTALMSEIRDFFIKTLDDAEGGIKFMMARLSNMLKSKDLSIYELLRSQELHPQ-YY 322
                    ||:.||..:...|     .:.|.:....|.:.::::..|..::||:.....:.. |:
Mouse   903 --------CFSHLMKRMGQNF-----PSGGAMDSHFANMRSLIQILDSELFELMHQNGDYTHFYF 954

  Fly   323 SFRWLTLLLSQEFPLPDVLRIWDSVFADEQRFD---FLIKICCSMILIQREAILEN--DFASNVK 382
            .:||..|...:|....||..:|:.::| .:|..   |::.|..:::...||.|.:|  ||...:|
Mouse   955 CYRWFLLDFKRELLYEDVFAVWEVIWA-ARRISSEHFVLFIALALVEAYREIIRDNNMDFTDIIK 1018

Fly 383 382
Mouse 1019 1018

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	42/192 (22%)
Sgsm2	NP_001361617.1	RUN	42..185	CDD:367169
		PH_RUTBC	256..424	CDD:275431
		TBC	<838..1006	CDD:214540	42/193 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810