DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GAPsec and AT4G13730

DIOPT Version :9

Sequence 1:	NP_648245.2	Gene:	GAPsec / 38987	FlyBaseID:	FBgn0035916	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_193109.1	Gene:	AT4G13730 / 827007	AraportID:	AT4G13730	Length:	449	Species:	Arabidopsis thaliana

Alignment Length:	413	Identity:	161/413 - (38%)
Similarity:	229/413 - (55%)	Gaps:	75/413 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VKEFEDVLAGPQ-------DLIDLKQLRKLAFNGVPDVQSFRALSWKLLLGYLGPRRSSWTTTLA 65
            |...|||....|       .:||||:|||:|..|:||....|::.|||||.||.|.||.|::.||
plant    91 VSSVEDVSRKAQVVAELSKKVIDLKELRKIASQGLPDDAGIRSIVWKLLLDYLSPDRSLWSSELA 155

  Fly    66 QKRALYKQFIEELVLPPGHSSNRASVD-GGDGD--KVDSGG------VGLQDHPLSEGPESAWNT 121
            :||:.||||.|||::.|...:.:.... |||.:  |::|.|      :..:|||||.|..|.||.
plant   156 KKRSQYKQFKEELLMNPSEVTRKMDKSKGGDSNDPKIESPGALSRSEITHEDHPLSLGTTSLWNN 220

  Fly   122 FFNDNEFLLQIDKDVRRLCPDISFFQQPTDYPCEIVVHSKGEHGRRLHERVVPAVLSSANVERKG 186
            ||.|.|.|.||::||.|..||:.||...:
plant   221 FFKDTEVLEQIERDVMRTHPDMHFFSGDS------------------------------------ 249

  Fly   187 LGMTKINLITKRSVENYAAMEEGQEAHWEVVQRILFIYAKLNPGQGYVQGMNEIVGPIYYVMASD 251
                             |..:..|:|    ::.||.|:||||||..||||||||:.||:|:..:|
plant   250 -----------------AVAKSNQDA----LKNILTIFAKLNPGIRYVQGMNEILAPIFYIFKND 293

  Fly   252 PDLTYRAHAEADCFFCFTALMSEIRDFFIKTLDDAEGGIKFMMARLSNMLKSKDLSIYELLR-SQ 315
            ||....|:||:|.||||..|||..||.|.:.||::..||::.:.|||.:||..|..::..|. :.
plant   294 PDKGNAAYAESDAFFCFVELMSGFRDNFCQQLDNSVVGIRYTITRLSLLLKHHDEELWRHLEVTT 358

  Fly   316 ELHPQYYSFRWLTLLLSQEFPLPDVLRIWDSVFAD-EQRFDFLIKICCSMILIQREAILENDFAS 379
            :::||:|:|||:||||:|||...:.|.|||::.:| |...:.|::|||:|:::.|..:|..||.|
plant   359 KINPQFYAFRWITLLLTQEFNFVESLHIWDTLLSDPEGPQETLLRICCAMLILVRRRLLAGDFTS 423

  Fly   380 NVKLLQNYPPIDINVVIAHAGSL 402
            |:||||||||.:|:.::..|..|
plant   424 NLKLLQNYPPTNISHMLYVADKL 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	76/183 (42%)
AT4G13730	NP_193109.1	RabGAP-TBC	229..417	CDD:278964	85/244 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1396
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10068
Inparanoid	1	1.050	300	1.000	Inparanoid score	I786
OMA	1	1.010	-	-		QHG54276
OrthoDB	1	1.010	-	-		D683074at2759
OrthoFinder	1	1.000	-	-		FOG0001234
OrthoInspector	1	1.000	-	-		otm2964
orthoMCL	1	0.900	-	-		OOG6_102218
Panther	1	1.100	-	-	LDO	PTHR22957
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4286
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840