DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GAPsec and Tbc1d9

DIOPT Version :9

Sequence 1:	NP_648245.2	Gene:	GAPsec / 38987	FlyBaseID:	FBgn0035916	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001104774.1	Gene:	Tbc1d9 / 71310	MGIID:	1918560	Length:	1264	Species:	Mus musculus

Alignment Length:	241	Identity:	61/241 - (25%)
Similarity:	91/241 - (37%)	Gaps:	74/241 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   176 VLSSANVER-------KGL---GMTKINLITK-------RSVENYAAMEEGQEAHWEVVQRILFI 223
            :||.|..|:       :||   .|.|.||.|:       ||:..:.|.:  .|.....::|:|..
Mouse   527 LLSGAINEKATHPGYYEGLVEKSMGKYNLATEEIERDLHRSLPEHPAFQ--NEMGIAALRRVLTA 589

  Fly   224 YAKLNPGQGYVQGMNEIVGPIYYVMASDPDLTYRAHAEADCFFCFTALMSEIRDFFIKTLDDAEG 288
            ||..||..||.|.|| ||..:..:.|.          |.:.|:...||...:...:..|
Mouse   590 YAFRNPNIGYCQAMN-IVTSVLLLYAK----------EEEAFWLLVALCERMLPDYYNT------ 637

  Fly   289 GIKFMMARLSNMLKSKDLSIYELLRSQELHPQYY------------SFRW-LTLLLSQEFPLPDV 340
                   |:...|  .|..::|.| :::..||.|            |..| |||.|| ..|....
Mouse   638 -------RVVGAL--VDQGVFEEL-ARDYVPQLYDCMQDLGVISTISLSWFLTLFLS-VMPFESA 691

  Fly   341 LRIWDSVFADEQRFDFLIKICCSMILIQREAILENDFASNVKLLQN 386
            :.:.|..|.:.      ||:...:.|    |:|:    :||..|.|
Mouse   692 VVVVDCFFYEG------IKVIFQLAL----AVLD----ANVDKLLN 723

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	49/201 (24%)
Tbc1d9	NP_001104774.1	PH-GRAM1_TCB1D9_TCB1D9B	157..255	CDD:275420
		PH-GRAM2_TCB1D9_TCB1D9B	304..399	CDD:270161
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	410..456
		TBC	512..722	CDD:214540	59/238 (25%)
		EFh	<893..923	CDD:298682
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1119..1162
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810