Protein Alignment GAPsec and Tbc1d8

DIOPT Version :10

• Sequence 1: NP_648245.2
• Gene: GAPsec / 38987
• FlyBaseID: FBgn0035916
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: XP_006244913.1
• Gene: Tbc1d8 / 680133
• RGDID: 1595491
• Length: 1150
• Species: Rattus norvegicus
• Alignment Length: 330
• Identity: 68/330 - (20%)
• Similarity: 115/330 - (34%)
• Gaps: 102/330 - (30%)

  Fly    76 EELVLPPGHSSNRASVDGGDGDKVDSGGVGLQD-------HPL----------SEGPE------- 116
            :::..|..:|::..:...||.:.|.|.....::       ||.          |:.|:
  Rat   424 DDMASPVFYSTSICTDKFGDLEMVSSQSSEEREKEKSPLPHPEPLTAVFQQSGSQSPDSRLSREQ 488

  Fly   117 ---SAWNTFFND---NEFLLQIDKDVRRL----CPD-------ISFFQQPTDYPCEIVVHSKGEH 164
               |.||..|.:   ...:.:.:| :|:|    .|:       :.|....||     :....|.:
  Rat   489 IKISLWNDHFAEYGRTVCMFRTEK-IRKLVAMGIPESLRGRLWLLFSDAVTD-----LASHPGYY 547

  Fly   165 GRRLHERVVPAVLSSANVERKGLGMTKINLITKRSVENYAAMEEGQEAHWEVVQRILFIYAKLNP 229
            |..:.:.:....|.:..:||.          ..||:..:.|.:  .|.....::|:|..||..||
  Rat   548 GNLVEQSLGRCCLVTEEIERD----------LHRSLPEHPAFQ--NETGIAALRRVLTAYAHRNP 600

  Fly   230 GQGYVQGMNEIVGPIYYVMASDPDLTYRAHAEADCFFCFTALMSE-IRDFFIKTLDDAEGGIKFM 293
            ..||.|.||.:...:         |.|....||  |:...|:... :.|:|...:..|:
  Rat   601 KIGYCQSMNILTSVL---------LLYAKEEEA--FWLLVAVCERMLPDYFNHRVIGAQ------ 648

  Fly   294 MARLSNMLKSKDLSIYELLRSQELHPQY------------YSFRW-LTLLLSQEFPLPDVLRIWD 345
                      .|.|::|.|..:.| |:.            .|..| |||.|| ..||...:.:.|
  Rat   649 ----------VDQSVFEELIKEHL-PELAEHMSDLSALASISLSWFLTLFLS-IMPLESAVNVVD 701

  Fly   346 SVFAD 350
            ..|.|
  Rat   702 CFFYD 706

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	42/174 (24%)
Tbc1d8	XP_006244913.1	PH-GRAM1_TBC1D8	171..269	CDD:270156
		PH-GRAM2_TBC1D8	311..406	CDD:270160
		TBC	520..726	CDD:214540	51/233 (22%)