DRSC/TRiP Functional Genomics Resources

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Protein Alignment GAPsec and Tbc1d15

DIOPT Version :9

Sequence 1:NP_648245.2 Gene:GAPsec / 38987 FlyBaseID:FBgn0035916 Length:403 Species:Drosophila melanogaster
Sequence 2:XP_006514020.1 Gene:Tbc1d15 / 66687 MGIID:1913937 Length:688 Species:Mus musculus


Alignment Length:387 Identity:84/387 - (21%)
Similarity:152/387 - (39%) Gaps:111/387 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    21 LIDLKQLRKLAFNGVPDVQSFRALSWKLLLGYLGPRRSSWTTTLAQKRALYKQFIEELVLPPGHS 85
            |:.::.:::..|.|... .|.|..:||.||||.     .|.:|..::..|.||..:|..      
Mouse   332 LVAVESMKQKIFRGGLS-HSLRKQAWKFLLGYF-----PWDSTKEERTQLQKQKTDEYF------ 384

  Fly    86 SNRASVDGGDGDKVDSGGVGLQDHPLSEGPESAWNTFFNDNEFLLQIDKDVRRLCPDISFFQQPT 150
                             .:.||...:||..|.. |:...|...|  |:|||.|......|: :..
Mouse   385 -----------------RMKLQWKSVSEAQEKR-NSRLRDYRSL--IEKDVNRTDRTNKFY-EGQ 428

  Fly   151 DYPCEIVVHSKGEHGRRLHERVVPAVLSSANVERKGLGMTKINLITKRSVENYAAMEEGQEAHWE 215
            |.|..|::|.                                                       
Mouse   429 DNPGLILLHD------------------------------------------------------- 438

  Fly   216 VVQRILFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDLTYRAHAEADCFFCFTALMSEIRDFFI 280
                ||..|...:...||||||::::.|:.|||.:          |.|.|:||.:.|.::...| 
Mouse   439 ----ILMTYCMYDFDLGYVQGMSDLLSPLLYVMEN----------EVDAFWCFASYMDQMHQNF- 488

  Fly   281 KTLDDAEGGIKFMMARLSNMLKSKDLSIYELLRSQELHPQYYSFRWLTLLLSQEFPLPDVLRIWD 345
               ::...|:|..:.:||.:|:..|......|.||:....|:.||||.:...:||...|:||:|:
Mouse   489 ---EEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFLDILRLWE 550

  Fly   346 SVFADEQRFDFLIKICCSMILIQREAILENDFASNVKLLQNY----PPIDINVVIAHAGSLA 403
            .::.:....:|.:.:||:::..:::.|:...:..| ::|::.    ..||:..::..|.:::
Mouse   551 VMWTELPCKNFHLLLCCAILESEKQQIMAKHYGFN-EILKHINELSMKIDVEDILCKAEAIS 611

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GAPsecNP_648245.2 TBC <191..373 CDD:214540 43/181 (24%)
Tbc1d15XP_006514020.1 DUF3548 10..211 CDD:371881
TBC 343..578 CDD:214540 77/340 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5210
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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