Protein Alignment GAPsec and TBC1D15

DIOPT Version :9

• Sequence 1: NP_648245.2
• Gene: GAPsec / 38987
• FlyBaseID: FBgn0035916
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: XP_006719627.1
• Gene: TBC1D15 / 64786
• HGNCID: 25694
• Length: 699
• Species: Homo sapiens
• Alignment Length: 387
• Identity: 82/387 - (21%)
• Similarity: 154/387 - (39%)
• Gaps: 111/387 - (28%)

  Fly    21 LIDLKQLRKLAFNGVPDVQSFRALSWKLLLGYLGPRRSSWTTTLAQKRALYKQFIEELVLPPGHS 85
            ::::..::::.|.|... .:.|..:||.||||.     .|.:|..::..|.||..:|..
Human   340 ILNVDNMKQMIFRGGLS-HALRKQAWKFLLGYF-----PWDSTKEERTQLQKQKTDEYF------ 392

  Fly    86 SNRASVDGGDGDKVDSGGVGLQDHPLSEGPESAWNTFFNDNEFLLQIDKDVRRLCPDISFFQQPT 150
                             .:.||...:|:..|.. |:...|...|  |:|||.|......|: :..
Human   393 -----------------RMKLQWKSISQEQEKR-NSRLRDYRSL--IEKDVNRTDRTNKFY-EGQ 436

  Fly   151 DYPCEIVVHSKGEHGRRLHERVVPAVLSSANVERKGLGMTKINLITKRSVENYAAMEEGQEAHWE 215
            |.|..|::|.
Human   437 DNPGLILLHD------------------------------------------------------- 446

  Fly   216 VVQRILFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDLTYRAHAEADCFFCFTALMSEIRDFFI 280
                ||..|...:...||||||::::.|:.|||.:          |.|.|:||.:.|.::...|
Human   447 ----ILMTYCMYDFDLGYVQGMSDLLSPLLYVMEN----------EVDAFWCFASYMDQMHQNF- 496

  Fly   281 KTLDDAEGGIKFMMARLSNMLKSKDLSIYELLRSQELHPQYYSFRWLTLLLSQEFPLPDVLRIWD 345
               ::...|:|..:.:||.:|:..|......|.||:....|:.||||.:...:||...|:||:|:
Human   497 ---EEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFLDILRLWE 558

  Fly   346 SVFADEQRFDFLIKICCSMILIQREAILENDFASNVKLLQNY----PPIDINVVIAHAGSLA 403
            .::.:....:|.:.:||:::..:::.|:|..:..| ::|::.    ..||:..::..|.:::
Human   559 VMWTELPCTNFHLLLCCAILESEKQQIMEKHYGFN-EILKHINELSMKIDVEDILCKAEAIS 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	43/181 (24%)
TBC1D15	XP_006719627.1	DUF3548	19..227	CDD:192931
		TBC	351..586	CDD:214540	75/340 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810