DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GAPsec and tbc1d9

DIOPT Version :9

Sequence 1:	NP_648245.2	Gene:	GAPsec / 38987	FlyBaseID:	FBgn0035916	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	XP_692034.2	Gene:	tbc1d9 / 563578	ZFINID:	ZDB-GENE-060810-33	Length:	1248	Species:	Danio rerio

Alignment Length:	239	Identity:	56/239 - (23%)
Similarity:	83/239 - (34%)	Gaps:	74/239 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   189 MTKINLITK-------RSVENYAAMEEGQEAHWEVVQRILFIYAKLNPGQGYVQGMNEIVGPIYY 246
            |.|.||.|:       ||:..:.|.:  .|.....::|:|..||..||..||.|.|| ||..:..
Zfish   548 MGKYNLATEEIERDLHRSLPEHPAFQ--NEMGIAALRRVLTAYAFRNPNIGYCQAMN-IVTSVLL 609

  Fly   247 VMASDPDLTYRAHAEADCFFCFTALMSEIRDFFIKTLDDAEGGIKFMMARLSNMLKSKDLSIYEL 311
            :.|.          |.:.|:...|:...:...:..|             |:...|  .|..::|.
Zfish   610 LYAK----------EEEAFWLLVAMCERMLPDYYNT-------------RVVGAL--VDQGVFEE 649

  Fly   312 LRSQELH-PQYY------------SFRW-LTLLLSQEFPLPDVLRIWDSVFADEQRFDFLIKICC 362
            |  ..:| ||.|            |..| |||.|| ..|....:.:.|..|.:.      ||:..
Zfish   650 L--AHVHVPQLYDCMQALGVISTISLSWFLTLFLS-VMPFESAVVVVDCFFYEG------IKVIF 705

  Fly   363 SMILIQREAILE-----NDFASNVKLLQNY-----------PPI 390
            .:.|...:|.:.     .|....:.:|..|           |||
Zfish   706 QLALSVLDANIHQLLGCKDDGEAMTILGRYLDSVTNKDSTLPPI 749

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	49/202 (24%)
tbc1d9	XP_692034.2	PH-GRAM1_TCB1D9_TCB1D9B	154..252	CDD:275420
		PH-GRAM2_TCB1D9_TCB1D9B	301..396	CDD:270161
		TBC	510..720	CDD:214540	50/208 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810