DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GAPsec and tbc1d13

DIOPT Version :9

Sequence 1:	NP_648245.2	Gene:	GAPsec / 38987	FlyBaseID:	FBgn0035916	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001107894.1	Gene:	tbc1d13 / 561380	ZFINID:	ZDB-GENE-080204-86	Length:	414	Species:	Danio rerio

Alignment Length:	396	Identity:	197/396 - (49%)
Similarity:	272/396 - (68%)	Gaps:	15/396 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SIFKARVKEFEDVLAGPQDLIDLKQLRKLAFNGVPDVQSFRALSWKLLLGYLGPRRSSWTTTLAQ 66
            |.::.|::||:  ||..:..:|||.||:|.|:|:|.....|:|.||:||.||.|.::.|.|.|.:
Zfish     3 SSYRNRIQEFK--LALSEQQVDLKALRELCFSGIPCEGGIRSLCWKILLNYLPPDQALWETFLEK 65

  Fly    67 KRALYKQFIEELVLPPGHSSNRASVDGGDGDKVDSGGVGLQDHPLSEGPESAWNTFFNDNEFLLQ 131
            :|.:|.||:.|:::.||.:.....|...|        |.|:||||:..|:|.|||:|.|||.|||
Zfish    66 QRDVYAQFLREMIIQPGIAKANLGVSRED--------VTLEDHPLNPNPDSRWNTYFKDNEVLLQ 122

  Fly   132 IDKDVRRLCPDISFFQQPTDYPCEIVVHSKGEHGRRLHERVVPAVLSSANVERKGLGMTKINLIT 196
            ||||||||.||::|||:|||:||::::..:.|: ..|..||....|.:..|.|...|:|.::...
Zfish   123 IDKDVRRLYPDMAFFQRPTDFPCQLILDPQNEY-ETLRRRVEQTTLKAQTVNRNRSGVTNVSSPG 186

  Fly   197 KR----SVENYAAMEEGQEAHWEVVQRILFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDLTYR 257
            |.    ....||.:..|.|||||||:||||||||||||..|||||||||||:||..|:||:..::
Zfish   187 KALHLYPSNEYAVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGPVYYTFATDPNSQWK 251

  Fly   258 AHAEADCFFCFTALMSEIRDFFIKTLDDAEGGIKFMMARLSNMLKSKDLSIYELLRSQELHPQYY 322
            .|||||.|||||.||||.||.|||:|||::.||.|.|..:.:.||.||..:|..|:.|.:.|||:
Zfish   252 EHAEADTFFCFTNLMSENRDNFIKSLDDSQCGITFKMESVFSRLKQKDTELYIRLQEQNIKPQYF 316

  Fly   323 SFRWLTLLLSQEFPLPDVLRIWDSVFADEQRFDFLIKICCSMILIQREAILENDFASNVKLLQNY 387
            :||||||||||||.||||:|||||:|:.:.||:|||.:||:|:::.|:.:|..||.:|::|||:|
Zfish   317 TFRWLTLLLSQEFLLPDVIRIWDSLFSHQDRFEFLIPVCCAMLILIRDQLLAGDFTTNMRLLQDY 381

  Fly   388 PPIDIN 393
            |..|::
Zfish   382 PISDVH 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	106/185 (57%)
tbc1d13	NP_001107894.1	TBC	32..367	CDD:214540	174/343 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H10068
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D350831at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010