DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GAPsec and Sgsm1

DIOPT Version :9

Sequence 1:	NP_648245.2	Gene:	GAPsec / 38987	FlyBaseID:	FBgn0035916	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	XP_006535185.1	Gene:	Sgsm1 / 52850	MGIID:	107320	Length:	1148	Species:	Mus musculus

Alignment Length:	402	Identity:	82/402 - (20%)
Similarity:	152/402 - (37%)	Gaps:	100/402 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 EDVLAGPQDLIDLKQLRKLAF----NGVPDVQSFRALSWKLLLGYLGPRRSSWTTTLAQKRALYK 72
            |..|:....::|.::.....|    :.|.|.||..|.:.:    ...||.........:...|..
Mouse   784 EPSLSTEDSVLDAQRSLPAVFRPGDSSVEDGQSSEATTSR----DEAPREELAVQDSLESDLLAN 844

  Fly    73 QFIEELVLPPGH------SSNRASVDG--GDGDKVDSGGVGLQDHPLSEGPESAWNTFFNDNEFL 129
            :.:||.:..||.      ..:.|.:||  |:.||                |..|      |:|..
Mouse   845 ESLEEFMSIPGSLDVALPEKDGAVMDGWPGEADK----------------PSRA------DSEDN 887

  Fly   130 LQIDKDVRRLCPDISFFQQPTDYPCEIVVHSKGEHGRRLHERVVPAVLSSANVERKGLGMTKI-- 192
            |..:.::..|.|.::..                            ||.||||.|...:..:.:
Mouse   888 LSEEPEMESLFPALASL----------------------------AVTSSANNEASPVSSSGVTY 924

  Fly   193 --NLITKRSVENYAAMEEGQ---EAHW-------EVVQRILFIYAKLNPGQGYVQGMNEIVGPIY 245
              .|:...:|..:...::.|   .::|       |.::.|:..|...:...||||||.:::.|:.
Mouse   925 SPELLDLYTVNLHRIEKDVQRCDRSYWYFTAANLEKLRNIMCSYIWQHIEIGYVQGMCDLLAPLL 989

  Fly   246 YVMASDPDLTYRAHAEADCFFCFTALMSEIRDFFIKTLDDAEGGIKFMMARLSNMLKSKDLSIYE 310
            .::..          ||..|.|||.||..:...|     ...|.:....|.:.::::..|..::|
Mouse   990 VILDD----------EALAFSCFTELMKRMNQNF-----PHGGAMDTHFANMRSLIQILDSELFE 1039

  Fly   311 LLRSQELHPQ-YYSFRWLTLLLSQEFPLPDVLRIWDSVFADE--QRFDFLIKICCSMILIQREAI 372
            |:.....:.. |:.:||..|...:|....||..:|::::|.:  ....:::.|..:::.:.|:.|
Mouse  1040 LMHQNGDYTHFYFCYRWFLLDFKRELVYDDVFSVWETIWAAKHVSSAHYVLFIALALVEVYRDII 1104

  Fly   373 LEN--DFASNVK 382
            |||  ||...:|
Mouse  1105 LENNMDFTDIIK 1116

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	39/198 (20%)
Sgsm1	XP_006535185.1	RUN	44..186	CDD:367169
		PH_RUTBC	254..425	CDD:275431
		TBC	<936..1105	CDD:214540	37/183 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810