DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GAPsec and Tbc1d13

DIOPT Version :9

Sequence 1:	NP_648245.2	Gene:	GAPsec / 38987	FlyBaseID:	FBgn0035916	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	XP_575106.2	Gene:	Tbc1d13 / 499768	RGDID:	1591937	Length:	400	Species:	Rattus norvegicus

Alignment Length:	405	Identity:	204/405 - (50%)
Similarity:	278/405 - (68%)	Gaps:	15/405 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SIFKARVKEFEDVLAGPQDLIDLKQLRKLAFNGVPDVQSFRALSWKLLLGYLGPRRSSWTTTLAQ 66
            |:.|:|:.:|:|||..|.  |.|::||:|:|:|:|.....|.|.||:||.||...|.||.:.||:
  Rat     3 SLHKSRIADFQDVLKEPS--IVLEKLRELSFSGIPCEGGLRCLCWKILLNYLPLERDSWDSILAK 65

  Fly    67 KRALYKQFIEELVLPPGHSSNRASVDGGDGDKVDSGGVGLQDHPLSEGPESAWNTFFNDNEFLLQ 131
            :|.||.||:.|:::.||.:.....|...|        |..:||||:..|:|.|||:|.|||.|||
  Rat    66 QRGLYSQFLREMIIQPGIAKANMGVSRED--------VTFEDHPLNPNPDSRWNTYFKDNEVLLQ 122

  Fly   132 IDKDVRRLCPDISFFQQPTDYPCEIVVHSKGEHGRRLHERVVPAVLSSANVERKGLGMTKINLIT 196
            ||||||||||||||||:.|:|||.:::..:.|. ..|.:||....|.|..|.|...|:|.::...
  Rat   123 IDKDVRRLCPDISFFQRATEYPCLLILDPQNEF-ETLRKRVEQTTLKSQTVARNRSGVTNMSSPH 186

  Fly   197 KR----SVENYAAMEEGQEAHWEVVQRILFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDLTYR 257
            |.    ::..|..:..|.|||||||:||||||||||||..|||||||||||:||..|:||:..::
  Rat   187 KNNAPSALNEYEVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWK 251

  Fly   258 AHAEADCFFCFTALMSEIRDFFIKTLDDAEGGIKFMMARLSNMLKSKDLSIYELLRSQELHPQYY 322
            .|||||.|||||.||:||||.|||:|||::.||.:.|.::.:.||.||:.:|..|:.|.:.||::
  Rat   252 EHAEADTFFCFTNLMAEIRDNFIKSLDDSQCGITYKMEKVYSTLKEKDVELYLKLQEQSIKPQFF 316

  Fly   323 SFRWLTLLLSQEFPLPDVLRIWDSVFADEQRFDFLIKICCSMILIQREAILENDFASNVKLLQNY 387
            :||||||||||||.||||:|||||:|||..|||||:.:||:|:::.||.:|:.||..|::|||:|
  Rat   317 AFRWLTLLLSQEFLLPDVIRIWDSLFADGNRFDFLLLVCCAMLILIREQLLKGDFTVNMRLLQDY 381

  Fly   388 PPIDINVVIAHAGSL 402
            |..|:..::..|..|
  Rat   382 PISDVCKILQKAKEL 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	106/185 (57%)
Tbc1d13	XP_575106.2	TBC	32..367	CDD:214540	178/343 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	218	1.000	Domainoid score	I2577
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10068
Inparanoid	1	1.050	411	1.000	Inparanoid score	I1804
OMA	1	1.010	-	-		QHG54276
OrthoDB	1	1.010	-	-		D350831at33208
OrthoFinder	1	1.000	-	-		FOG0001234
OrthoInspector	1	1.000	-	-		oto97957
orthoMCL	1	0.900	-	-		OOG6_102218
Panther	1	1.100	-	-	LDO	PTHR22957
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4286
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840