DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GAPsec and CG42795

DIOPT Version :9

Sequence 1:	NP_648245.2	Gene:	GAPsec / 38987	FlyBaseID:	FBgn0035916	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001287272.1	Gene:	CG42795 / 41252	FlyBaseID:	FBgn0261928	Length:	3213	Species:	Drosophila melanogaster

Alignment Length:	450	Identity:	87/450 - (19%)
Similarity:	144/450 - (32%)	Gaps:	151/450 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 QLRKLAFNGVPDVQSFRALSWK-------------LLLGYLGPRRSSWTTTLAQKRALYKQFIEE 77
            ||.:||...|.|..|...|..:             |:||||..|.......|.:.:.:..:|:..
  Fly    45 QLAQLASGMVGDRSSLERLDVRKLIDVCAILKVEILMLGYLLERVLVARDRLQRHQEVLCEFVTA 109

  Fly    78 LVL---------------PPGH--------------------------SSNRASVD--------- 92
            :::               ||..                          |:||:...
  Fly   110 VLIVESDDAQPKMRFSLSPPPQKAITSARLTSPTKNSLSSNNTITTPGSNNRSPSSTKTTMLTRN 174

  Fly    93 -GGDGDKVDSGGVGLQDHPLSEGPESAWNTFFNDNEFLLQIDKDVRRLCPDISFFQQPTDYPCEI 156
             ||.|....:.|.|......:...:.|.:.:   |::|..: |.|.||         |...|
  Fly   175 GGGHGTSPTASGSGHAPSATAAADDEATSDY---NQWLHAM-KLVARL---------PGGTP--- 223

  Fly   157 VVHSKGEHGRRLHERVVPAVLSSANVE------------------------RKGLGMTKINLITK 197
                 .|..|:|...:....|.|.||:                        .|.|..|..||.|.
  Fly   224 -----PEFRRKLWLSLADKYLKSKNVDWAQQREKCFCEEWREDDEELGIQIVKDLHRTGSNLCTG 283

  Fly   198 RSVENYAAMEEGQEAHWEVVQRILFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDLTYRAHAEA 262
            .:    .::.:.:      ::|||..||:.||..||.||.|.:...|..||..:         |.
  Fly   284 PA----GSINQAK------LKRILLGYARYNPEVGYCQGFNMLGALILQVMDKE---------EE 329

  Fly   263 DCFFCFTALMSEI--RDFFIKTLD--DAEGGI--KFMMARLSNMLKSKDLSIYELLRSQ-----E 316
            :.......|:..:  ..:|..::.  .|:.|:  :.|..||..:.|       .|.|.|     .
  Fly   330 ESMKVMIYLVEGVLPTGYFYGSMGGLQADMGVFRELMQTRLPRLAK-------HLQRLQGPVENA 387

  Fly   317 LHP---QYYSFRWLTLLLSQEFPLPDVLRIWDSVFADEQRFDFLIKICCSMILIQREAIL 373
            ..|   ..::.:|...:.....|:..|||:||.|..:..  |.|::....:..:..|.::
  Fly   388 FEPPLTNVFTMQWFLTMFCTCLPMSCVLRVWDLVLIEGS--DVLLRTALVLWSLLEERVI 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	42/195 (22%)
CG42795	NP_001287272.1	RabGAP-TBC	268..443	CDD:278964	44/202 (22%)
		DUF4682	560..684	CDD:292361
		DBP	1112..1415	CDD:289157
		SWIRM-assoc_2	<2376..2482	CDD:293105
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456572
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740