DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GAPsec and plx

DIOPT Version :9

Sequence 1:	NP_648245.2	Gene:	GAPsec / 38987	FlyBaseID:	FBgn0035916	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001163511.1	Gene:	plx / 40704	FlyBaseID:	FBgn0261261	Length:	1572	Species:	Drosophila melanogaster

Alignment Length:	400	Identity:	83/400 - (20%)
Similarity:	144/400 - (36%)	Gaps:	110/400 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LKQLRKLAFNGVPDVQSFRALSWKLLLGYLGPRRSSWTTTLAQKRALYKQFIEELVLPPGHSSN- 87
            |..:||.|..|..|....|.|               |.|.:.|...|.:...|..:|....:.|
  Fly   838 LSPMRKPAKRGKRDAAELREL---------------WRTAIRQTIMLNRMETENAMLQARQNENE 887

  Fly    88 --RASVDGGD-----------------------GDKVDSGGVGLQDHPLSEG-PES----AWNTF 122
              |..:|..:                       |:|.|...:|   |.:..| |.|    .| ||
  Fly   888 LKRIKLDYEEIVPCDKQLIERWEQIIERNSTQIGNKKDPKVLG---HAIRTGVPRSKRGDVW-TF 948

  Fly   123 FNDNEFLLQIDKDVRRLCPDISFFQQPTDYPCEIVVHSKGEHGRRLH---ERVVPAVLSSANVER 184
            ..:...:.....|.:|. |:.       :.|..:::....||...:.   .|..|    :....:
  Fly   949 LAEQHSMNTAPVDTKRF-PNF-------NTPYHMLLKHLTEHQHAIFIDLGRTFP----NHQFYK 1001

  Fly   185 KGLGMTKINLITKRSVENYAAMEEGQEAHWEVVQRILFIYAKLNPGQGYVQGMNEIVGPIYYVMA 249
            ..||:.:::|.                       .:|..|:.|:|..||.||:..|.|.:  ::.
  Fly  1002 DPLGLGQLSLF-----------------------NLLKAYSILDPELGYCQGLGFICGVL--LLH 1041

  Fly   250 SDPDLTYRAHAEADCFFCFTALMSEIRDFFIKTLDDAEGGIKFMMA--RLSNMLKSKDLSIYELL 312
            .|         ||:.|.....||.. |:...|.|.|.:   ||.:.  :||.::|.....:|..|
  Fly  1042 CD---------EANSFQLLKHLMFR-RNMRTKYLPDMK---KFQLQLYQLSRLVKDHLPDLYVWL 1093

  Fly   313 RSQELHPQYYSFRWLTLLLSQEFPLPDVLRIWDSVFADEQRFDFLIKICCSMILIQREAILENDF 377
            ...::.|..|:..|:..:.|.:|||..|.|::|.:|.:..  |.:.|...:::.:.::.:|..|
  Fly  1094 DQNDVSPTLYAAPWILTVFSSQFPLGFVARVFDLLFLESS--DVIFKFAIALLSVHKQQLLAKD- 1155

  Fly   378 ASNVKLLQNY 387
              |.:.:.:|
  Fly  1156 --NFEEIMDY 1163

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	41/183 (22%)
plx	NP_001163511.1	PTB_TBC1D1_like	301..601	CDD:269967
		DUF3350	835..880	CDD:288663	13/56 (23%)
		TBC	933..1152	CDD:214540	57/271 (21%)
		RILP-like	<1176..1267	CDD:304877
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456545
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22957
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940